Human ZFP91 Recombinant Protein – Cat# MBS1418336

E3 Ubiquitin-Protein Ligase ZFP91 (ZFP91) Human Recombinant Protein

Name: ZFP91 Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1418336
Price: 385 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1418336

MBS1418336 is a recombinant protein targeting ZFP91. Also known as Recombinant Human E3 ubiquitin-protein ligase ZFP91 (ZFP91). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

E3 ubiquitin-protein ligase ZFP91 (ZFP91), Recombinant Protein

Full Product Name

Recombinant Human E3 ubiquitin-protein ligase ZFP91 (ZFP91)

Product Gene Name

ZFP91 recombinant protein

Product Synonym Gene Name

ZFP91; ZNF757; FKSG11

Product Synonym Names

E3 ubiquitin-protein ligase ZFP91; EC=6.3.2.-; Zinc finger protein 757; Zinc finger protein 91 homolog; Zfp-91

Sequence

ETPKPRRKSG KVKEEKEKKE IKVEVEVEVK EEENEIREDE EPPRKRGRRR KDDKSPRLPK RRKKPPIQYV RCEMEGCGTV LAHPRYLQHH IKYQHLLKKK YVCPHPSCGR LFRLQKQLLR HAKHHTDQRD YICEYCARAF KSSHNLAVHR MIHTGEKPLQ CEICGFTCRQ KASLNWHMKK HDADSFYQFS CNICGKKFEK KDSVVAHKAK SHPEVLIAEA LAANAGALIT STDILGTNPE SLTQPSDGQG LPLLPEPLGN STSGECLLLE AEGMSKSYCS GTERVSLMAD GKIFVGSGSS GGTEGLVMNS DILGATTEVL IEDSDSAGP

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

59,571 Da

Sequence Positions

242-570. Partial

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for Q96JP5

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ZFP91 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ZFP91. It may not necessarily be applicable to this product.

NCBI GI #

308081964

NCBI GeneID

80829

NCBI Accession #

NP_001183980.1

UniProt Primary Accession #

Q96JP5

UniProt Secondary Accession #

Q86V47; Q96JP4; Q96QA3; A6NHC4; A8MSG7

UniProt Related Accession #

Q96JP5

GenBank Nucleotide #

NM_001197051.1

NCBI Official Full Name

E3 ubiquitin-protein ligase ZFP91 isoform 2

NCBI Official Synonym Full Names

ZFP91 zinc finger protein

NCBI Official Symbol

ZFP91

NCBI Official Synonym Symbols

PZF; DMS-8; DSM-8; FKSG11; ZFP-91; ZNF757

UniProt Protein Name

E3 ubiquitin-protein ligase ZFP91

UniProt Synonym Protein Names

Zinc finger protein 757; Zinc finger protein 91 homolog; Zfp-91

Protein Family

E3 ubiquitin-protein ligase

UniProt Gene Name

ZFP91

UniProt Synonym Gene Names

ZNF757; Zfp-91

UniProt Entry Name

ZFP91_HUMAN

NCBI Protein Information

E3 ubiquitin-protein ligase ZFP91; zinc finger protein 757; penta zinc finger protein; zinc finger protein 91 homolog; zinc finger protein homologous to Zfp91 in mouse; drug resistance-associated sequence in melanoma 8

NCBI Summary for ZFP91

The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2. [provided by RefSeq, Oct 2010]

UniProt Comments for ZFP91

ZFP91: Atypical E3 ubiquitin-protein ligase that mediates 'Lys- 63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non- canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.-; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 11q12

Cellular Component: nucleus

Molecular Function: nucleic acid binding; metal ion binding; ubiquitin-protein ligase activity; ligase activity

Biological Process: activation of NF-kappaB-inducing kinase

Research Articles on ZFP91

1. These data clearly indicate that ZFP91 is a key regulator in LIGHT-induced activation of non-canonical NF-kappaB pathway in LTbetaR signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with ZFP91 recombinant protein

Disease Name	Pubmed Publications
Cell Transformation, Neoplastic Antibodies	>1 publications with ZFP91 and Cell Transformation, Neoplastic
Inflammation Antibodies	>1 publications with ZFP91 and Inflammation
Hyperplasia Antibodies	>1 publications with ZFP91 and Hyperplasia
Necrosis Antibodies	>1 publications with ZFP91 and Necrosis

Organs/Tissues associated with ZFP91 recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Marrow Antibodies	>2 publications with ZFP91 and Bone Marrow
Bone Antibodies	>2 publications with ZFP91 and Bone
Muscle Antibodies	>1 publications with ZFP91 and Muscle
Prostate Antibodies	>1 publications with ZFP91 and Prostate
Bladder Antibodies	>1 publications with ZFP91 and Bladder
Testis Antibodies	>1 publications with ZFP91 and Testis