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Cysteine Protease ATG4B (ATG4B) Chicken Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1420331

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and… More details

$1130 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cysteine protease ATG4B (ATG4B), Recombinant Protein
Full Product Name
Recombinant Chicken Cysteine protease ATG4B (ATG4B)
Product Gene Name
ATG4B recombinant protein
Product Synonym Gene Name
ATG4B
Sequence
MDAATLTYDT LRFEYEDFPE TKEPVWILGR KYSVFTEKEE ILLDVTSRLW FTYRKNFPAI GGTGPTSDTG WGCMLRCGQM IFAQALVCRH LGRDWRWIKG KRQTDNYFSV LNAFIDKKDS YYSIHQIAQM GVGEGKSIGQ WYGPNTVAQV LKKLATFDTW SSLAVHIAMD NTVVMEEIRR LCQSNFSCAG AAACPAVEAD VLYNGYPEEA GVRDKLSLWK PLVLLIPLRL GLTEINEAYI ETLKHCFMMP QSLGVIGGKP NSAHYFIGYV GEELIYLDPH TTQPAVEPSD SGCLPDESFH CQHPPCRMSI AELDPSIAVG FFCHTEEDFN DWCHQIKKLS LVRGALPMFE LVERQPSHFS NPDVLNLTPD SSDADRLERF FDSEDEDFEI LSL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
38,598 Da
Sequence Positions
1-393, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q6PZ02
Species
Chicken
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ATG4B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATG4B purchase

MBS1420331 is a recombinant protein targeting ATG4B. Also known as Recombinant Chicken Cysteine protease ATG4B (ATG4B). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for ATG4B. It may not necessarily be applicable to this product.

NCBI GI #
47087191
NCBI GeneID
404750
NCBI Accession #
NP_998738.1
UniProt Primary Accession #
Q6PZ02
UniProt Secondary Accession #
Q5ZK72
UniProt Related Accession #
Q6PZ02
GenBank Nucleotide #
NM_213573.1
NCBI Official Full Name
cysteine protease ATG4B
NCBI Official Synonym Full Names
autophagy related 4B cysteine peptidase
NCBI Official Symbol
ATG4B
NCBI Official Synonym Symbols
APG4B
UniProt Protein Name
Cysteine protease ATG4B
UniProt Synonym Protein Names
Autophagy-related cysteine endopeptidase 2B; Autophagin-2B; cAut2B; Autophagy-related protein 4 homolog B
Protein Family
Cysteine protease
UniProt Gene Name
ATG4B
UniProt Synonym Gene Names
APG4B; AUT2B; Autophagin-2B; cAut2B
NCBI Protein Information
cysteine protease ATG4B

UniProt Comments for ATG4B

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE). Has also an activity of delipidating enzyme for the PE-conjugated forms ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ATG4B recombinant protein

 Products by Pathway  Pathway Diagram
 Regulation Of Autophagy Pathway antibodies  Regulation Of Autophagy Pathway Diagram
 Regulation Of Autophagy Pathway antibodies  Regulation Of Autophagy Pathway Diagram

Diseases associated with ATG4B recombinant protein

 Disease Name  Pubmed Publications
 Infection Antibodies  >4 publications with ATG4B and Infection
 Neoplasms Antibodies  >3 publications with ATG4B and Neoplasms
 Postoperative Complications Antibodies  >2 publications with ATG4B and Postoperative Complications
 Reperfusion Injury Antibodies  >2 publications with ATG4B and Reperfusion Injury
 Inflammation Antibodies  >1 publications with ATG4B and Inflammation
 Bone Diseases Antibodies  >1 publications with ATG4B and Bone Diseases

Organs/Tissues associated with ATG4B recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Other Antibodies  >13 publications with ATG4B and Other
 Liver Antibodies  >2 publications with ATG4B and Liver
 Brain Antibodies  >2 publications with ATG4B and Brain
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