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Protein Lin-7 Homolog B (LIN7B) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1420548

MBS1420548 is a recombinant protein targeting LIN7B. Also known as Recombinant Human Protein lin-7 homolog B (LIN7B). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$860 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Protein lin-7 homolog B (LIN7B), Recombinant Protein
Full Product Name
Recombinant Human Protein lin-7 homolog B (LIN7B)
Product Gene Name
LIN7B recombinant protein
Product Synonym Gene Name
LIN7B
Sequence
MAALVEPLGL ERDVSRAVEL LERLQRSGEL PPQKLQALQR VLQSRFCSAI REVYEQLYDT LDITGSAEIR AHATAKATVA AFTASEGHAH PRVVELPKTD EGLGFNIMGG KEQNSPIYIS RVIPGGVADR HGGLKRGDQL LSVNGVSVEG EQHEKAVELL KAAQGSVKLV VRYTPRVLEE MEARFEKMRS ARRRQQHQSY SSLESRG
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
15,620 Da
Sequence Positions
1-207, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
612331
3D Structure
ModBase 3D Structure for Q9HAP6
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LIN7B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LIN7B. It may not necessarily be applicable to this product.

NCBI GI #
817473368
NCBI GeneID
64130
NCBI Accession #
NP_001295348.1
UniProt Primary Accession #
Q9HAP6
UniProt Related Accession #
Q9HAP6
GenBank Nucleotide #
NM_001308419.1
NCBI Official Full Name
protein lin-7 homolog B isoform 2
NCBI Official Synonym Full Names
lin-7 homolog B, crumbs cell polarity complex component
NCBI Official Symbol
LIN7B
NCBI Official Synonym Symbols
MALS2; VELI2; LIN-7B; MALS-2
UniProt Protein Name
Protein lin-7 homolog B
UniProt Synonym Protein Names
Mammalian lin-seven protein 2; MALS-2; Vertebrate lin-7 homolog 2; Veli-2; hVeli2
Protein Family
Protein
UniProt Gene Name
LIN7B
UniProt Synonym Gene Names
MALS2; VELI2; Lin-7B; hLin7B; MALS-2; Veli-2; hVeli2
NCBI Protein Information
protein lin-7 homolog B

UniProt Comments for LIN7B

Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface ().
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Research Articles on LIN7B

1. functional deficiency in Lin-7B could be implicated in clinical phenotypes in some autism spectrum disorders patients through bringing about abnormal cortical architecture

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LIN7B recombinant protein

 Reference Product  PubMed Publications
 CASK recombinant protein  >2 publications with LIN7B and CASK
 BAIAP2 recombinant protein  >1 publications with LIN7B and BAIAP2
 DLG4 recombinant protein  >1 publications with LIN7B and DLG4
 RTKN recombinant protein  >1 publications with LIN7B and RTKN
 APBA1 recombinant protein  >1 publications with LIN7B and APBA1

Diseases associated with LIN7B recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with LIN7B and Nervous System Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with LIN7B and Neurobehavioral Manifestations
 Heart Diseases Antibodies  >1 publications with LIN7B and Heart Diseases
 Cognition Disorders Antibodies  >1 publications with LIN7B and Cognition Disorders
 Cardiovascular Diseases Antibodies  >1 publications with LIN7B and Cardiovascular Diseases

Organs/Tissues associated with LIN7B recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with LIN7B and Brain
 Eye Antibodies  >2 publications with LIN7B and Eye
 Testis Antibodies  >1 publications with LIN7B and Testis
 Embryonic Tissue Antibodies  >1 publications with LIN7B and Embryonic Tissue
 Uncharacterized Tissue Antibodies  >1 publications with LIN7B and Uncharacterized Tissue
 Heart Antibodies  >1 publications with LIN7B and Heart
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