Human FGF 22 Recombinant Protein – Cat# MBS142304

Fibroblast Growth Factor-22 (FGF 22) Human Recombinant Protein

Name: FGF 22 Recombinant Protein; Fibroblast Growth Factor-22; Human; MyBioSource
Brand: MyBioSource
SKU: MBS142304
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS142304

Description: Fibroblast Growth Factor-22 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids and having a molecular mass of 17.3 kDa. The FGF-22 is purified by chromatographic… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fibroblast Growth Factor-22 (FGF 22), Recombinant Protein

Full Product Name

Recombinant Human Fibroblast Growth Factor-22

Product Gene Name

FGF 22 recombinant protein

Product Synonym Names

FGF 22 Human; Fibroblast Growth Factor-22 Human Recombinant; Fibroblast growth factor 22; FGF-22

Sequence

MTPSASRGPR SYPHLEGDVR WRRLFSSTHF FLRVDPGGRV QGTRWRHGQD SILEIRSVHV GVVVIKAVSS GFYVAMNRRG RLYGSRLYTV DCRFRERIEE NGHNTYASQR WRRRGQPMFL ALDRRGGPRP GGRTRRYHLS AHFLPVLVS

Host

E Coli

Form/Format

The sterile protein powder is lyophilized with no additives.
Sterile Filtered white lyophilized powder.

Purity/Purification

Greater than 97.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Preparation and Storage

Lyophilized Fibroblast Growth Factor 22 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution FGF-22 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Molecular Weight

19,663 Da

OMIM

605831

3D Structure

ModBase 3D Structure for Q9HCT0

Solubility

It is recommended to reconstitute the lyophilized Fibroblast Growth Factor-22 sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Product Categories/Family for FGF 22 recombinant protein

Cytokines and Growth Factors; Growth Factors; Fibroblast Growth Factor

Other Notes

Small volumes of FGF 22 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF 22 purchase

MBS142304 is a recombinant protein targeting FGF 22. Also known as Recombinant Human Fibroblast Growth Factor-22. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for FGF 22. It may not necessarily be applicable to this product.

NCBI GI #

10190672

NCBI GeneID

27006

NCBI Accession #

NP_065688.1

UniProt Primary Accession #

Q9HCT0

UniProt Secondary Accession #

B2RPH4

UniProt Related Accession #

Q9HCT0

GenBank Nucleotide #

NM_020637.1

NCBI Official Full Name

fibroblast growth factor 22 isoform 1

NCBI Official Synonym Full Names

fibroblast growth factor 22

NCBI Official Symbol

FGF22

UniProt Protein Name

Fibroblast growth factor 22

Protein Family

Fibroblast growth factor

UniProt Gene Name

FGF22

UniProt Synonym Gene Names

FGF-22

UniProt Entry Name

FGF22_HUMAN

NCBI Protein Information

fibroblast growth factor 22; FGF-22

NCBI Summary for FGF 22

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

UniProt Comments for FGF 22

FGF22: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. Belongs to the heparin-binding growth factors family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi apparatus; extracellular space; cell surface; nucleolus; extracellular region

Molecular Function: growth factor activity; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; insulin receptor signaling pathway; innate immune response; cell differentiation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FGF 22 recombinant protein

Reference Product	PubMed Publications
FGF7 recombinant protein	>12 publications with FGF 22 and FGF7
FGF10 recombinant protein	>9 publications with FGF 22 and FGF10
FGF3 recombinant protein	>6 publications with FGF 22 and FGF3
FGFR2 recombinant protein	>6 publications with FGF 22 and FGFR2
FGFR1 recombinant protein	>5 publications with FGF 22 and FGFR1
FGF9 recombinant protein	>4 publications with FGF 22 and FGF9
FGF1 recombinant protein	>4 publications with FGF 22 and FGF1
FGFR4 recombinant protein	>2 publications with FGF 22 and FGFR4
FGF6 recombinant protein	>2 publications with FGF 22 and FGF6
FGFR3 recombinant protein	>1 publications with FGF 22 and FGFR3

Pathways associated with FGF 22 recombinant protein

Products by Pathway	Pathway Diagram
Activated Point Mutants Of FGFR2 Pathway antibodies	Activated Point Mutants Of FGFR2 Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies	Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
DAP12 Interactions Pathway antibodies	DAP12 Interactions Pathway Diagram
DAP12 Signaling Pathway antibodies	DAP12 Signaling Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Downstream Signal Transduction Pathway antibodies	Downstream Signal Transduction Pathway Diagram
Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies	Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
Downstream Signaling Of Activated FGFR Pathway antibodies	Downstream Signaling Of Activated FGFR Pathway Diagram
FGFR Ligand Binding And Activation Pathway antibodies	FGFR Ligand Binding And Activation Pathway Diagram

Diseases associated with FGF 22 recombinant protein

Disease Name	Pubmed Publications
Seizures Antibodies	>2 publications with FGF 22 and Seizures
Necrosis Antibodies	>1 publications with FGF 22 and Necrosis
Brain Diseases Antibodies	>1 publications with FGF 22 and Brain Diseases
Breast Neoplasms Antibodies	>1 publications with FGF 22 and Breast Neoplasms
Nervous System Diseases Antibodies	>1 publications with FGF 22 and Nervous System Diseases
Lung Neoplasms Antibodies	>1 publications with FGF 22 and Lung Neoplasms

Organs/Tissues associated with FGF 22 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>6 publications with FGF 22 and Brain