Human POSTN Recombinant Protein – Cat# MBS142328

Periostin (POSTN) Human Recombinant Protein

Name: POSTN Recombinant Protein; Periostin; Human; MyBioSource
Brand: MyBioSource
SKU: MBS142328
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Popular Catalog #: MBS142328

Description: The OSF2 His-Tagged Fusion Protein Human is produced in E Coli, and its molecular weight is 75 kDa protein containing 648 amino acid residues of the human OSF-2 and 23 additional amino acid residues - HisTag, Xa - cleavage site.Introduction:… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Periostin (POSTN), Recombinant Protein

Full Product Name

Recombinant Human Periostin

Product Gene Name

POSTN recombinant protein

Product Synonym Names

Periostin Human; Periostin Human Recombinant; OSF-2; Periostin; Osteoblast Specific Factor 2; PN OSF-2; PDLPOSTN; POSTN; MGC119510; MGC119511; PN; RP11-412K4.1; Periostin

Sequence

MGHHHHH HHH HHSSGHIEGR HMRNNH YDKI LAHSRIRGRD QGPNVCALQQ ILGTKKKYFS TCKNWYKKSI CGQKTTVLYE CCPGYMRMEG MKGCPAVLPI DHVYGTLGIV GATTTQRYSD ASKLREEIEG KGSFTYFAPS NEAWDNLDSD IRRGLESNVN VELLNALHSH MINKRMLTKD LKNGMIIPSM YNNLGLFINH YPNGVVTVNC ARIIHGNQIA TNGVVHVIDR VLTQIGTSIQ DFIEAEDDLS SFRAAAITSD ILEALGRDGH FTLFAPTNEA FEKLPRGVLE RFMGDKVASE ALMKYHILNT LQCSESIMGG AVFETLEGNT IEIGCDGDSI TVNGIKMVNK KDIVTNNGVI HLIDQVLIPD SAKQVIELAG KQQTTFTDLV AQLGLASALR PDGEYTLLAP VNNAFSDDTL SMVQRLLKLI LQNHILKVKV GLNELYNGQI LETIGGKQLR VFVYRTAVCI ENSCMEKGSK QGRNGAIHIF REIIKPAEKS LHEKLKQDKR FSTFLSLLEA ADLKELLTQP GDWTLFVPTN DAFKGMTSEE KEILIRDKNA LQNIILYHLT PGVFIGKGFE PGVTNILKTT QGSKIFLKEV NDTLLVNELK SKESDIMTTN GVIHVVDKLL YPADTPVGND QLLEILNKLI KYIQIKFVRG STFKEIPVTV Y

Form/Format

Filtered (0.4 um) and lyophilized from 0.5 mg/ml in 0.05M Acetate buffer pH-4.
Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Preparation and Storage

Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

Molecular Weight

80,357 Da

OMIM

608777

3D Structure

ModBase 3D Structure for Q15063

Source

E.coli

Solubility

It is recommended to add 0.1M Acetate buffer pH4 to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10 ug/ml. In higher concentrations the solubility of this antigen is limited. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Product Categories/Family for POSTN recombinant protein

Cytokines and Growth Factors; Growth Factors

Other Notes

Small volumes of POSTN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for POSTN purchase

MBS142328 is a recombinant protein targeting POSTN. Also known as Recombinant Human Periostin.

Additional Details

NCBI/Uniprot data below describe general gene information for POSTN. It may not necessarily be applicable to this product.

NCBI GI #

209862911

NCBI GeneID

10631

NCBI Accession #

NP_001129406.1

UniProt Primary Accession #

Q15063

UniProt Secondary Accession #

Q15064; Q29XZ0; Q3KPJ5; Q5VSY5; Q8IZF9; B1ALD8; C0IMJ1; C0IMJ2; C0IMJ4; D2KRH7; F5H628

UniProt Related Accession #

Q15063

GenBank Nucleotide #

NM_001135934.1

NCBI Official Full Name

periostin isoform 2

NCBI Official Synonym Full Names

periostin, osteoblast specific factor

NCBI Official Symbol

POSTN

NCBI Official Synonym Symbols

PN; OSF2; OSF-2; PDLPOSTN; periostin

UniProt Protein Name

Periostin

UniProt Synonym Protein Names

Osteoblast-specific factor 2; OSF-2

Protein Family

Periostin

UniProt Gene Name

POSTN

UniProt Synonym Gene Names

OSF2; PN; OSF-2

UniProt Entry Name

POSTN_HUMAN

NCBI Protein Information

periostin; osteoblast specific factor 2 (fasciclin I-like); periodontal ligament-specific periostin

NCBI Summary for POSTN

This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

UniProt Comments for POSTN

POSTN: Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Cell adhesion; Secreted, signal peptide; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 13q13.3

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; trans-Golgi network

Molecular Function: heparin binding; protein binding; cell adhesion molecule binding

Biological Process: tissue development; extracellular matrix organization and biogenesis; regulation of Notch signaling pathway; cell adhesion; skeletal development

Research Articles on POSTN

1. the secreted cell adhesion protein periostin is markedly upregulated in livers of obese patients, along with reduced expression of PPARalpha

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with POSTN recombinant protein

Reference Product	PubMed Publications
TGFB1 recombinant protein	>33 publications with POSTN and TGFB1
COL1A1 recombinant protein	>7 publications with POSTN and COL1A1
DCN recombinant protein	>7 publications with POSTN and DCN
COL3A1 recombinant protein	>7 publications with POSTN and COL3A1
COL1A2 recombinant protein	>5 publications with POSTN and COL1A2
FN1 recombinant protein	>5 publications with POSTN and FN1
CLCA1 recombinant protein	>4 publications with POSTN and CLCA1
SERPINB2 recombinant protein	>4 publications with POSTN and SERPINB2
COL5A2 recombinant protein	>3 publications with POSTN and COL5A2
LUM recombinant protein	>3 publications with POSTN and LUM

Diseases associated with POSTN recombinant protein

Disease Name	Pubmed Publications
Fibrosis Antibodies	>70 publications with POSTN and Fibrosis
Inflammation Antibodies	>57 publications with POSTN and Inflammation
Neoplasm Metastasis Antibodies	>40 publications with POSTN and Neoplasm Metastasis
Disease Models, Animal Antibodies	>39 publications with POSTN and Disease Models, Animal
Adenocarcinoma Antibodies	>32 publications with POSTN and Adenocarcinoma
Breast Neoplasms Antibodies	>27 publications with POSTN and Breast Neoplasms
Lung Neoplasms Antibodies	>25 publications with POSTN and Lung Neoplasms
Myocardial Infarction Antibodies	>21 publications with POSTN and Myocardial Infarction
Heart Failure Antibodies	>19 publications with POSTN and Heart Failure
Nervous System Diseases Antibodies	>15 publications with POSTN and Nervous System Diseases

Organs/Tissues associated with POSTN recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>121 publications with POSTN and Bone
Muscle Antibodies	>77 publications with POSTN and Muscle
Heart Antibodies	>71 publications with POSTN and Heart
Connective Tissue Antibodies	>63 publications with POSTN and Connective Tissue
Lung Antibodies	>56 publications with POSTN and Lung
Mouth Antibodies	>54 publications with POSTN and Mouth
Vascular Antibodies	>52 publications with POSTN and Vascular
Embryonic Tissue Antibodies	>36 publications with POSTN and Embryonic Tissue
Skin Antibodies	>35 publications with POSTN and Skin
Liver Antibodies	>24 publications with POSTN and Liver