• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Poly (U)-Binding-Splicing Factor PUF60 (PUF60) Pongo Abelii Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1424038

MBS1424038 is a recombinant protein targeting PUF60. Also known as Recombinant Pongo abelii Poly (U)-binding-splicing factor PUF60 (PUF60), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Poly (U)-binding-splicing factor PUF60 (PUF60), Recombinant Protein
Full Product Name
Recombinant Pongo abelii Poly (U)-binding-splicing factor PUF60 (PUF60), partial
Product Gene Name
PUF60 recombinant protein
Product Synonym Gene Name
PUF60
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
55,427 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q5R469
Species
Pongo abelii (Sumatran orangutan)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PUF60 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PUF60. It may not necessarily be applicable to this product.

NCBI GI #
197100546
NCBI GeneID
100174042
NCBI Accession #
NP_001127017.1
UniProt Primary Accession #
Q5R469
UniProt Secondary Accession #
Q5RFS8
UniProt Related Accession #
Q5R469
GenBank Nucleotide #
NM_001133545.1
NCBI Official Full Name
poly(U)-binding-splicing factor PUF60
NCBI Official Symbol
PUF60
UniProt Protein Name
Poly(U)-binding-splicing factor PUF60
UniProt Synonym Protein Names
60 kDa poly(U)-binding-splicing factor
Protein Family
Poly(U)-binding-splicing factor
UniProt Gene Name
PUF60
NCBI Protein Information
poly(U)-binding-splicing factor PUF60

UniProt Comments for PUF60

DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3'-splice site and pyrimidine tract in a cooperative manner with U2AF2. Involved in apoptosis induction when overexpressed in HeLa cells. Modulates alternative splicing of several mRNAs. Binds to relaxed DNA of active promoter regions. Binds to the pyrimidine tract and 3'-splice site regions of pre-mRNA; binding is enhanced in presence of U2AF2. Binds to Y5 RNA in association with TROVE2. Binds to poly(U) RNA ().
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PUF60 recombinant protein

 Products by Pathway  Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram

Diseases associated with PUF60 recombinant protein

 Disease Name  Pubmed Publications
 Ovarian Diseases Antibodies  >1 publications with PUF60 and Ovarian Diseases
 Neoplasm Metastasis Antibodies  >1 publications with PUF60 and Neoplasm Metastasis
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000