PPP4C Recombinant Protein – Cat# MBS142407

Phosphatase 4 (PPP4C) Recombinant Protein

Name: PPP4C Recombinant Protein; Phosphatase 4; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS142407
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS142407

Description: 800x600 800x600 800x600 PPP4C Human Recombinant produced in E Coli is a single polypeptide chain containing 330 amino acids (1-307) and having a molecular mass of 37.5kDa. PPP4C is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Phosphatase 4 (PPP4C), Recombinant Protein

Full Product Name

Recombinant Human Protein Phosphatase 4 Catalytic subunit

Product Gene Name

PPP4C recombinant protein

Product Synonym Names

PPP4C Human; Protein Phosphatase 4 Catalytic subunit Human Recombinant; 800x600 800x600 Serine/threonine-protein phosphatase 4 catalytic subunit; PP4; PP4C; PPH3; PPP4; PPX; PPP4C; Protein Phosphatase 4 Catalytic subunit; Protein phosphatase X; PP-X; Pp4

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMAE ISDL DRQIEQLRRC ELIKESEVKA LCAKAREILV EESNVQRVDS PVTVCGDIHG QFYDLKELFR VGGDVPETNY LFMGDFVDRG FYSVETFLLL LALKVRYPDR ITLIRGNHES RQITQVYGFY DECLRKYGSV TVWRYCTEIF DYLSLSAIID GKIFCVHGGL SPSIQTLDQI RTIDRKQEVP HDGPMCDLLW SDPEDTTGWG VSPRGAGYLF GSDVVAQFNA ANDIDMICRA HQLVMEGYKW HFNETVLTVW SAPNYCYRCG NVAAILELDE HLQKDFIIFE AAPQETRGIP SKKPVADYFL .

Host

E Coli

Form/Format

The PPP4C solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

Purity/Purification

Greater than 90% as determined by SDS-PAGE.

Preparation and Storage

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

OMIM

602035

3D Structure

ModBase 3D Structure for P60510

Physcial Appearance

Sterile filtered colorless solution

Product Categories/Family for PPP4C recombinant protein

Enzymes; Phosphatase

Other Notes

Small volumes of PPP4C recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPP4C purchase

MBS142407 is a recombinant protein targeting PPP4C. Also known as Recombinant Human Protein Phosphatase 4 Catalytic subunit. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP4C. It may not necessarily be applicable to this product.

NCBI GI #

4506027

NCBI GeneID

5531

NCBI Accession #

NP_002711.1

UniProt Primary Accession #

P60510

UniProt Secondary Accession #

P33172

UniProt Related Accession #

P60510

GenBank Nucleotide #

NM_002720.2

NCBI Official Full Name

serine/threonine-protein phosphatase 4 catalytic subunit isoform 1

NCBI Official Synonym Full Names

protein phosphatase 4, catalytic subunit

NCBI Official Symbol

PPP4C

NCBI Official Synonym Symbols

PP4; PPX; PP-X; PP4C; PPH3; PPP4

UniProt Protein Name

Serine/threonine-protein phosphatase 4 catalytic subunit

UniProt Synonym Protein Names

Protein phosphatase X; PP-X

Protein Family

Phospholipase

UniProt Gene Name

PPP4C

UniProt Synonym Gene Names

PPP4; PPX; PP4C; Pp4; PP-X

UniProt Entry Name

PP4C_HUMAN

NCBI Protein Information

serine/threonine-protein phosphatase 4 catalytic subunit; protein phosphatase 4 (formerly X), catalytic subunit; protein phosphatase X, catalytic subunit

UniProt Comments for PPP4C

PPP4C: a Ser/Thr phosphatase. A positive regulator of HPK1 and the HPK1-JNK signaling pathway. Mediates TNF-alpha-induced degradation of IRS-4 and plays a role in NF-kappaB p65 Thr dephosphorylation. Holoenzyme consists at least of a catalytic subunit PPP4C and a regulatory subunit PPP4R1.

Protein type: Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; microtubule organizing center; nucleus

Molecular Function: NF-kappaB-inducing kinase activity; protein binding; metal ion binding; protein serine/threonine phosphatase activity

Biological Process: dephosphorylation

Research Articles on PPP4C

1. PP4 and Wip1 are differentially required to counteract the p53-dependent cell cycle arrest in G1 and G2, by antagonizing early or late p53-mediated responses, respectively

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PPP4C recombinant protein

Reference Product	PubMed Publications
PPP4R2 recombinant protein	>2 publications with PPP4C and PPP4R2

Diseases associated with PPP4C recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>1 publications with PPP4C and Nervous System Diseases
Breast Neoplasms Antibodies	>1 publications with PPP4C and Breast Neoplasms

Organs/Tissues associated with PPP4C recombinant protein

Organ/Tissue Name	Pubmed Publications
Epididymis Antibodies	>1 publications with PPP4C and Epididymis
Muscle Antibodies	>1 publications with PPP4C and Muscle
Bone Antibodies	>1 publications with PPP4C and Bone
Nerve Antibodies	>1 publications with PPP4C and Nerve
Blood Antibodies	>1 publications with PPP4C and Blood
Mammary Gland Antibodies	>1 publications with PPP4C and Mammary Gland
Testis Antibodies	>1 publications with PPP4C and Testis
Brain Antibodies	>1 publications with PPP4C and Brain