Human CA3 Recombinant Protein – Cat# MBS142411

Carbonic Anhydrase III (CA3) Human Recombinant Protein

Name: CA3 Recombinant Protein; Carbonic Anhydrase III; Human; MyBioSource
Brand: MyBioSource
SKU: MBS142411
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS142411

Description: Carbonic anhydrase III Human Recombinant produced in E Coli, and having a molecular mass of 33.9 kDa. CAIII is expressed with an amino-terminal hexahistidine tag.The CA-III is purified by proprietary chromatographic techniques.Introduction:… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Carbonic Anhydrase III (CA3), Recombinant Protein

Full Product Name

Recombinant Human Carbonic Anhydrase III, His Tag

Product Gene Name

CA3 recombinant protein

Product Synonym Names

CAIII Human, His; Carbonic Anhydrase III Human Recombinant, His Tag; Car3; CAIII; Carbonic anhydrase 3; EC 4.2.1.1; Carbonic anhydrase III; Carbonate dehydratase III; CA-III; CA3 His

Host

E Coli

Form/Format

Supplied in 10mM Tris-HCl (pH 8), 250mM NaCl, 0.5mM DTT, 1.5mM Cysteine, and 50% Glycerol.
Sterile Filtered blue solution.

Purity/Purification

Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Preparation and Storage

CAIII although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Molecular Weight

29,557 Da

OMIM

114750

3D Structure

ModBase 3D Structure for P07451

Product Categories/Family for CA3 recombinant protein

Enzymes; Carbonic Anhydrase

Other Notes

Small volumes of CA3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CA3 purchase

MBS142411 is a recombinant protein targeting CA3. Also known as Recombinant Human Carbonic Anhydrase III, His Tag. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CA3. It may not necessarily be applicable to this product.

NCBI GI #

4885099

NCBI GeneID

761

NCBI Accession #

NP_005172.1

UniProt Primary Accession #

P07451

UniProt Secondary Accession #

O60842; B2R867; B3KUC8

UniProt Related Accession #

P07451

GenBank Nucleotide #

NM_005181.3

NCBI Official Full Name

carbonic anhydrase 3

NCBI Official Synonym Full Names

carbonic anhydrase III

NCBI Official Symbol

CA3

NCBI Official Synonym Symbols

Car3; CAIII

UniProt Protein Name

Carbonic anhydrase 3

UniProt Synonym Protein Names

Carbonate dehydratase III; Carbonic anhydrase III; CA-III

Protein Family

Carbonic anhydrase

UniProt Gene Name

CA3

UniProt Synonym Gene Names

CA-III

UniProt Entry Name

CAH3_HUMAN

NCBI Protein Information

carbonic anhydrase 3; CA-III; HEL-S-167mP; carbonate dehydratase III; carbonic anhydrase III, muscle specific; epididymis secretory sperm binding protein Li 167mP

NCBI Summary for CA3

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008]

UniProt Comments for CA3

CA3: Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family.

Protein type: Lyase; Energy Metabolism - nitrogen; EC 4.2.1.1

Chromosomal Location of Human Ortholog: 8q21.2

Cellular Component: cytosol

Molecular Function: carbonate dehydratase activity; zinc ion binding; nickel ion binding

Biological Process: response to ethanol; bicarbonate transport; response to oxidative stress; one-carbon compound metabolic process

Research Articles on CA3

1. Report that anti-CAIII antibodies may be useful for diagnosing microscopic polyangiitis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CA3 recombinant protein

Reference Product	PubMed Publications
POLE recombinant protein	>38 publications with CA3 and POLE
CCND1 recombinant protein	>6 publications with CA3 and CCND1
INS recombinant protein	>6 publications with CA3 and INS
CYP2E1 recombinant protein	>4 publications with CA3 and CYP2E1

Pathways associated with CA3 recombinant protein

Products by Pathway	Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Nitrogen Metabolism Pathway antibodies	Nitrogen Metabolism Pathway Diagram
Nitrogen Metabolism Pathway antibodies	Nitrogen Metabolism Pathway Diagram
Reversible Hydration Of Carbon Dioxide Pathway antibodies	Reversible Hydration Of Carbon Dioxide Pathway Diagram

Diseases associated with CA3 recombinant protein

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>2844 publications with CA3 and Brain Diseases
Central Nervous System Diseases Antibodies	>2784 publications with CA3 and Central Nervous System Diseases
Seizures Antibodies	>1233 publications with CA3 and Seizures
Disease Models, Animal Antibodies	>843 publications with CA3 and Disease Models, Animal
Learning Disorders Antibodies	>299 publications with CA3 and Learning Disorders
Cognition Disorders Antibodies	>174 publications with CA3 and Cognition Disorders
Necrosis Antibodies	>170 publications with CA3 and Necrosis
Prenatal Exposure Delayed Effects Antibodies	>98 publications with CA3 and Prenatal Exposure Delayed Effects
Inflammation Antibodies	>98 publications with CA3 and Inflammation
Prenatal Injuries Antibodies	>98 publications with CA3 and Prenatal Injuries

Organs/Tissues associated with CA3 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>9452 publications with CA3 and Brain
Nerve Antibodies	>1819 publications with CA3 and Nerve
Blood Antibodies	>720 publications with CA3 and Blood
Embryonic Tissue Antibodies	>96 publications with CA3 and Embryonic Tissue
Muscle Antibodies	>80 publications with CA3 and Muscle
Heart Antibodies	>70 publications with CA3 and Heart
Liver Antibodies	>56 publications with CA3 and Liver
Eye Antibodies	>47 publications with CA3 and Eye
Kidney Antibodies	>39 publications with CA3 and Kidney
Mouth Antibodies	>31 publications with CA3 and Mouth