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Threonyl T-RNA Synthetase (PL 7) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS142445

Description: Threonyl-tRNA Synthetase Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 83,312 Dalton. PL-7 is expressed with a -6xHis tag and purified by proprietary chromatographic techniques. More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Threonyl t-RNA Synthetase (PL 7), Recombinant Protein
Full Product Name
Recombinant Human Threonyl t-RNA Synthetase
Product Gene Name
Product Synonym Names
PL 7 Human; Threonyl-tRNA Synthetase Human Recombinant; Threonyl-tRNA synthetase cytoplasmic; EC 6.1.1.3; Threonine-tRNA ligase; ThrRS; MGC9344; PL-7; TARS
Host
Sf9 Insect Cells
Form/Format
PL-7 is supplied at 0.5mg/ml in 20mM HEPES buffer pH-8, 200mM sodium chloride, and 20% glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Concentration
0.3-0.8 ug/ml (depending on the type of ELISA plate and coating buffer).Suitable for biotinylation and iodination. (lot specific)
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Avoid multiple freeze-thaw cycles.
OMIM
187790
3D Structure
ModBase 3D Structure for P26639
Immunological Functions
1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test (checker-board analysis of positive/negative sera panels immuno-dot test).

Product Categories/Family for PL 7 recombinant protein

Other Notes

Small volumes of PL 7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PL 7 purchase

MBS142445 is a recombinant protein targeting PL 7. Also known as Recombinant Human Threonyl t-RNA Synthetase. Host: Sf9 Insect Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for PL 7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
threonine--tRNA ligase, cytoplasmic isoform 1
NCBI Official Synonym Full Names
threonyl-tRNA synthetase
NCBI Official Symbol
TARS
NCBI Official Synonym Symbols
ThrRS
UniProt Protein Name
Threonine--tRNA ligase, cytoplasmic
UniProt Synonym Protein Names
Threonyl-tRNA synthetase; ThrRS
UniProt Gene Name
TARS
UniProt Synonym Gene Names
ThrRS
UniProt Entry Name
SYTC_HUMAN
NCBI Protein Information
threonine--tRNA ligase, cytoplasmic; threonine tRNA ligase 1, cytoplasmic; threonyl-tRNA synthetase, cytoplasmic

NCBI Summary for PL 7

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family [provided by RefSeq, Jul 2008]
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UniProt Comments for PL 7

TARS: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family [provided by RefSeq, Jul 2008]

Protein type: Ligase; EC 6.1.1.3; Translation

Chromosomal Location of Human Ortholog: 5p13.2

Cellular Component: cytoplasm; cytosol; actin cytoskeleton

Molecular Function: threonine-tRNA ligase activity; protein homodimerization activity; ATP binding

Biological Process: tRNA aminoacylation for protein translation; translation; threonyl-tRNA aminoacylation; gene expression
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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