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Urate Oxidase (UOX) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS142453

Description: Urate Oxidase Recombinant produced in E Coli is a tetrameric, non-glycosylated polypeptide chain containing 302 amino acids, having a molecular formula of C1523H2383N417O462S7 and a molecular mass of 34,247 Dalton.The cDNA coding for… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Urate Oxidase (Uox), Active Protein
Full Product Name
Recombinant Urate Oxidase
Product Gene Name
Product Synonym Names
Urate Oxidase, Uricase, Urate Oxygen, Oxidoreductase, UOX, UO, EC 1.7.3.
Sequence
msavkaaryg kdnvrvykvh kdektgvqtv yemtvcvlle geietsytka dnsvivatds ikntiyitak qnpvtppelf gsilgthfie kynhihaahv nivchrwtrm didgkphphs firdseekrn vqvdvvegkg idiksslsgl tvlkstnsqf wgflrdeytt lketwdrils tdvdatwqwk nfsglqevrs hvpkfdatwa tarevtlktf aednsasvqa tmykmaeqil arqqlietve yslpnkhyfe idlswhkglq ntgknaevfa pqsdpnglik ctvgrsslks kl
Form/Format
Each 1.5mg Uricase contains 5mg sucrose, 25mg glycine, 0.1mg Tween-80, 13.6 mg Na2HPO4*12H2O and 0.33 mg NaH2PO4*2H2O.
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
Lyophilized Urate Oxidase although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Uricase should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Source
E. coli
Solubility
We highly recommend reconstituting the lyophilized Uricase in 50mM borate buffer containing 0.001%Triton X-100 and 1.0mM EDTA, pH 8.5 for activity assay.
Biological Activity
The specific activity was found to be 10U/mg.One Unit oxidizes one micromole of uric acid per minute at 25 degree C, at pH 8.5.

Product Categories/Family for Uox active protein

Other Notes

Small volumes of Uox active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Uox purchase

MBS142453 is an active protein targeting Uox. Also known as Recombinant Urate Oxidase.

Additional Details

NCBI/Uniprot data below describe general gene information for Uox. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
uricase
NCBI Official Synonym Full Names
urate oxidase
NCBI Official Symbol
Uox
NCBI Official Synonym Symbols
Uri; Uri2; UOX-2
UniProt Protein Name
Uricase
UniProt Synonym Protein Names
Urate oxidase
Protein Family
UniProt Gene Name
Uox
UniProt Entry Name
URIC_RAT
NCBI Protein Information
uricase; urate oxidase 2

NCBI Summary for Uox

catalyzes the hydrolysis of uric acid to allantoin in purine degradation [RGD, Feb 2006]

UniProt Comments for Uox

uricase: Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.

Protein type: EC 1.7.3.3; Oxidoreductase; Mitochondrial

Cellular Component: peroxisomal matrix; mitochondrion; peroxisome

Molecular Function: urate oxidase activity

Biological Process: urate catabolic process; purine base catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Uox active protein

Organs/Tissues associated with Uox active protein

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