Human SCT Synthetic Protein – Cat# MBS142666

Secretin (SCT) Human Synthetic Protein

Name: SCT Synthetic Protein; Secretin; Human; MyBioSource
Brand: MyBioSource
SKU: MBS142666
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS142666

Description: Secretin has a molecular formula of C130H220N44O41,a.a. sequence of H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg- Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 and having a Mw of 3055.4 Dalton.Introduction: Human Secretin… More details

$250 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Secretin (SCT), Synthetic Protein

Full Product Name

Human Secretin

Product Gene Name

SCT synthetic protein

Product Synonym Names

Secretin Human; Secretin Human; Secretin

Form/Format

The protein (1 mg/ml) was lyophilized with no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.

Purity/Purification

Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Preparation and Storage

Lyophilized Secretin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Secretin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Molecular Weight

13,016 Da

OMIM

182099

3D Structure

ModBase 3D Structure for P09683

Solubility

It is recommended to reconstitute the lyophilized Secretin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Product Categories/Family for SCT synthetic protein

Hormones; Hormones; Peptide Hormones

Other Notes

Small volumes of SCT synthetic protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCT purchase

MBS142666 is a synthetic protein targeting SCT. Also known as Human Secretin.

Additional Details

NCBI/Uniprot data below describe general gene information for SCT. It may not necessarily be applicable to this product.

NCBI GI #

11345450

NCBI GeneID

6343

NCBI Accession #

NP_068739.1

UniProt Primary Accession #

P09683

UniProt Related Accession #

P09683

GenBank Nucleotide #

NM_021920.2

NCBI Official Full Name

secretin preproprotein

NCBI Official Synonym Full Names

secretin

NCBI Official Symbol

SCT

UniProt Protein Name

Secretin

Protein Family

Secretin

UniProt Gene Name

SCT

UniProt Entry Name

SECR_HUMAN

NCBI Protein Information

secretin; prepro-secretin

NCBI Summary for SCT

Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion. [provided by RefSeq, Jul 2008]

UniProt Comments for SCT

SCT: Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach. Belongs to the glucagon family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: dentate gyrus development; visual learning; negative regulation of neuron apoptosis; pancreatic juice secretion

Research Articles on SCT

1. CD36 is a major mediator of FA-induced release of CCK and secretin. These peptides contribute to the role of CD36 in fat absorption and to its pleiotropic metabolic effects.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SCT synthetic protein

Reference Product	PubMed Publications
PTH synthetic protein	>37 publications with SCT and PTH
SCTR synthetic protein	>10 publications with SCT and SCTR
SST synthetic protein	>5 publications with SCT and SST
GHRH synthetic protein	>5 publications with SCT and GHRH
CALCR synthetic protein	>2 publications with SCT and CALCR
GCG synthetic protein	>2 publications with SCT and GCG
CALCA synthetic protein	>1 publications with SCT and CALCA

Pathways associated with SCT synthetic protein

Products by Pathway	Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Glucagon-type Ligand Receptors Pathway antibodies	Glucagon-type Ligand Receptors Pathway Diagram
Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies	Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with SCT synthetic protein

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>495 publications with SCT and Cardiovascular Diseases
Pain Antibodies	>165 publications with SCT and Pain
Inflammation Antibodies	>139 publications with SCT and Inflammation
Brain Diseases Antibodies	>116 publications with SCT and Brain Diseases
Kidney Diseases Antibodies	>106 publications with SCT and Kidney Diseases
Necrosis Antibodies	>98 publications with SCT and Necrosis
Heart Diseases Antibodies	>94 publications with SCT and Heart Diseases
Hemorrhage Antibodies	>85 publications with SCT and Hemorrhage
Hypertension Antibodies	>53 publications with SCT and Hypertension
Weight Loss Antibodies	>40 publications with SCT and Weight Loss

Organs/Tissues associated with SCT synthetic protein

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>23 publications with SCT and Testis