Non-Muscle Myosin-II Regulatory Light Chain (NMM) Human Active Protein

Description: Non-Muscle Myosin-II Regulatory Light Chain Human Recombinant full length expressed in E Coli.The NMM is purified by proprietary chromatographic techniques.

Introduction: Non muscle Myosins are required for cytokinesis at the end of cell division, when a contractile ring near the plasmalemma divides the cytoplasm of the daughter cells. They are involved in cytoplasmic streaming movements in tissues, and especially in activation of motile cells such as fibroblasts and macrophages. Activation of non-muscle myosin-II is achieved by phosphorylation of Ser33 in the motif KKRPQRATSN by a dedicated, Ca +2 Calmodulin regulated light chain kinase (MLCK).

Small volumes of NMM active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS142921 is an active protein targeting NMM. Also known as Recombinant Human Non-Muscle Myosin-II Regulatory Light Chain. Host: E Coli.