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HBS1-Like Protein (HBS1L) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1429438

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative… More details

$1520 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HBS1-like protein (HBS1L), Recombinant Protein
Full Product Name
Recombinant Human HBS1-like protein (HBS1L)
Product Gene Name
HBS1L recombinant protein
Product Synonym Gene Name
HBS1L
Sequence
MARHRNVRGY NYDEDFEDDD LYGQSVEDDY CISPSTAAQF IYSRRDKPSV EPVEEYDYED LKESSNSVSN HQLSGFDQAR LYSCLDHMRE VLGDAVPDEI LIEAVLKNKF DVQKALSGVL EQDRVQSLKD KNEATVSTGK IAKGKPVDSQ TSRSESEIVP KVAKMTVSGK KQTMGFEVPG VSSEENGHSF HTPQKGPPIE DAIASSDVLE TASKSANPPH TIQASEEQSS TPAPVKKSGK LRQQIDVKAE LEKRQGGKQL LNLVVIGHVD AGKSTLMGHM LYLLGNINKR TMHKYEQESK KAGKASFAYA WVLDETGEER ERGVTMDVGM TKFETTTKVI TLMDAPGHKD FIPNMITGAA QADVAVLVVD ASRGEFEAGF ETGGQTREHG LLVRSLGVTQ LAVAVNKMDQ VNWQQERFQE ITGKLGHFLK QAGFKESDVG FIPTSGLSGE NLITRSQSSE LTKWYKGLCL LEQIDSFKPP QRSIDKPFRL CVSDVFKDQG SGFCITGKIE AGYIQTGDRL LAMPPNETCT VKGITLHDEP VDWAAAGDHV SLTLVGMDII KINVGCIFCG PKVPIKACTR FRARILIFNI EIPITKGFPV LLHYQTVSEP AVIKRLISVL NKSTGEVTKK KPKFLTKGQN ALVELQTQRP IALELYKDFK ELGRFMLRYG GSTIAAGVVT EIKE
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
70,625 Da
Sequence Positions
1-684, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
612450
3D Structure
ModBase 3D Structure for Q9Y450
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of HBS1L recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HBS1L purchase

MBS1429438 is a recombinant protein targeting HBS1L. Also known as Recombinant Human HBS1-like protein (HBS1L). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for HBS1L. It may not necessarily be applicable to this product.

NCBI GI #
223555963
NCBI GeneID
10767
NCBI Accession #
NP_001138630.1
UniProt Primary Accession #
Q9Y450
UniProt Secondary Accession #
Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3; B7Z365
UniProt Related Accession #
Q9Y450
GenBank Nucleotide #
NM_001145158.1
NCBI Official Full Name
HBS1-like protein isoform 2
NCBI Official Synonym Full Names
HBS1 like translational GTPase
NCBI Official Symbol
HBS1L
NCBI Official Synonym Symbols
ERFS; HBS1; EF-1a; eRF3c; HSPC276
UniProt Protein Name
HBS1-like protein
UniProt Synonym Protein Names
ERFS
Protein Family
HBS1-like protein
UniProt Gene Name
HBS1L
UniProt Synonym Gene Names
HBS1; KIAA1038
NCBI Protein Information
HBS1-like protein

NCBI Summary for HBS1L

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, May 2009]
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Research Articles on HBS1L

1. Induction of ribosome rescue factors PELO and HBS1L is required to support protein synthesis when ABCE1 levels fall in platelets, including for hemoglobin production during blood cell development.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with HBS1L recombinant protein

 Reference Product  PubMed Publications
 MYB recombinant protein  >46 publications with HBS1L and MYB
 BCL11A recombinant protein  >28 publications with HBS1L and BCL11A
 HBG1 recombinant protein  >1 publications with HBS1L and HBG1

Pathways associated with HBS1L recombinant protein

 Products by Pathway  Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram

Diseases associated with HBS1L recombinant protein

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >3 publications with HBS1L and Cardiovascular Diseases
 Immune System Diseases Antibodies  >2 publications with HBS1L and Immune System Diseases
 Bone Diseases Antibodies  >1 publications with HBS1L and Bone Diseases
 Atherosclerosis Antibodies  >1 publications with HBS1L and Atherosclerosis
 Inflammation Antibodies  >1 publications with HBS1L and Inflammation

Organs/Tissues associated with HBS1L recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with HBS1L and Blood
 Nerve Antibodies  >1 publications with HBS1L and Nerve
 Uncharacterized Tissue Antibodies  >1 publications with HBS1L and Uncharacterized Tissue
 Heart Antibodies  >1 publications with HBS1L and Heart
 Brain Antibodies  >1 publications with HBS1L and Brain
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