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Tripartite Motif-Containing Protein 71 (TRIM71) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1429785

MBS1429785 is a recombinant protein targeting TRIM71. Also known as Recombinant Human Tripartite motif-containing protein 71 (TRIM71) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tripartite motif-containing protein 71 (TRIM71), Recombinant Protein
Full Product Name
Recombinant Human Tripartite motif-containing protein 71 (TRIM71) , partial
Product Gene Name
TRIM71 recombinant protein
Product Synonym Gene Name
TRIM71
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
93,385 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q2Q1W2
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TRIM71 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRIM71. It may not necessarily be applicable to this product.

NCBI GI #
84993742
NCBI GeneID
131405
NCBI Accession #
NP_001034200.1
UniProt Primary Accession #
Q2Q1W2
UniProt Related Accession #
Q2Q1W2
GenBank Nucleotide #
NM_001039111.2
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM71
NCBI Official Synonym Full Names
tripartite motif containing 71
NCBI Official Symbol
TRIM71
NCBI Official Synonym Symbols
LIN41; LIN-41
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM71
UniProt Synonym Protein Names
Protein lin-41 homolog; RING-type E3 ubiquitin transferase TRIM71Curated; Tripartite motif-containing protein 71
Protein Family
E3 ubiquitin-protein ligase
UniProt Gene Name
TRIM71
UniProt Synonym Gene Names
LIN41
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM71

NCBI Summary for TRIM71

The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase transition of the cell cycle. [provided by RefSeq, Dec 2015]

UniProt Comments for TRIM71

E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance (Probable). Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A (). In addition, participates in post-transcriptional mRNA repression in a miRNA independent mechanism (PubMed:23125361). Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1 (). Specific regulator of miRNA biogenesis. Binds to miRNA MIR29A hairpin and postranscriptionally modulates MIR29A levels, which indirectly regulates TET proteins expression (PubMed:28431233).
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Research Articles on TRIM71

1. TRIM71 acts through post-transcriptional repression of Lin28B and subsequent modulation of let-7-HMGA2 signaling during tumorigenesis to potentially function as a tumor suppressor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TRIM71 recombinant protein

 Products by Pathway  Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram

Diseases associated with TRIM71 recombinant protein

 Disease Name  Pubmed Publications
 Death Antibodies  >1 publications with TRIM71 and Death

Organs/Tissues associated with TRIM71 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >1 publications with TRIM71 and Embryonic Tissue
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