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Dnaj Homolog Subfamily C Member 10 (DNAJC10) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1430086

MBS1430086 is a recombinant protein targeting Dnajc10. Also known as Recombinant Mouse DnaJ homolog subfamily C member 10 (Dnajc10). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1625 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DnaJ homolog subfamily C member 10 (Dnajc10), Recombinant Protein
Full Product Name
Recombinant Mouse DnaJ homolog subfamily C member 10 (Dnajc10)
Product Gene Name
Dnajc10 recombinant protein
Product Synonym Gene Name
Dnajc10
Sequence
DQNFYSLLGV SKTASSREIR QAFKKLALKL HPDKNPNNPN AHGDFLKINR AYEVLKDEDL RKKYDKYGEK GLEDNQGGQY ESWSYYRYDF GIYDDDPEII TLERREFDAA VNSGELWFVN FYSPGCSHCH DLAPTWREFA KEVDGLLRIG AVNCGDDRML CRMKGVNSYP SLFIFRSGMA AVKYNGDRSK ESLVAFAMQH VRSTVTELST GNFVNAIETA FAAGVGWLIT FCSKGEDCLT SQTRLRLSGM LDGLVNVGWV DCDAQDSLCK SLDTTASTTA YFPPGATLND REKSSVLFLN SLDAKEIYME IIHNLPDFEL LSANQLEDRL AHHRWLVFFH FGKNENANDP ELKKLKTLLK NEHIQVGRFD CSSAPGICSD LYVFQPCLAV FKGQGTKEYE IHHGKKILYD ILAFAKESVN SHVTTLGPQN FPASDKEPWL VDFFAPWCPP CRALLPELRK ASTLLYGQLK VGTLDCTIHE GLCNMYNIQA YPTTVVFNQS SIHEYEGHHS AEQILEFIED LRNPSVVSLT PSTFNELVKQ RKHDEVWMVD FYSPWCHPCQ VLMPEWKRMA RTLTGLINVG SVDCQQYHSF CTQENVQRYP EIRFYPQKSS KAYQYHSYNG WNRDAYSLRS WGLGFLPQAS IDLTPQTFNE KVLQGKTHWV VDFYAPWCGP CQNFAPEFEL LARMIKGKVR AGKVDCQAYP QTCQKAGIKA YPSVKLYQYE RAKKSIWEEQ INSRDAKTIA ALIYGKLETL QSQVKRNKDE L
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
90,583 Da
Sequence Positions
33-793, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9DC23
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Dnajc10 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Dnajc10. It may not necessarily be applicable to this product.

NCBI GI #
119508443
NCBI GeneID
66861
NCBI Accession #
NP_077143.2
UniProt Primary Accession #
Q9DC23
UniProt Secondary Accession #
Q71S84; Q8CH78; Q8CIB0; Q99LV4; A2ASA2
UniProt Related Accession #
Q9DC23
GenBank Nucleotide #
NM_024181.2
NCBI Official Full Name
dnaJ homolog subfamily C member 10
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member C10
NCBI Official Symbol
Dnajc10
NCBI Official Synonym Symbols
JPDI; ERdj5; D2Ertd706e; 1200006L06Rik
UniProt Protein Name
DnaJ homolog subfamily C member 10
UniProt Synonym Protein Names
Endoplasmic reticulum DNA J domain-containing protein 5; ER-resident protein ERdj5; ERdj5; Endoplasmic reticulum DnaJ-PDI fusion protein 1; J domain-containing protein disulfide isomerase-like protein; J domain-containing PDI-like protein; JPDI
Protein Family
DnaJ homolog subfamily
UniProt Gene Name
Dnajc10
UniProt Synonym Gene Names
Erdj5; Jpdi; ER-resident protein ERdj5; ERdj5; J domain-containing PDI-like protein; JPDI
NCBI Protein Information
dnaJ homolog subfamily C member 10

UniProt Comments for Dnajc10

Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
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Research Articles on Dnajc10

1. These results identify ERdj5 as one of the master regulators of ER calcium homeostasis and thus shed light on the importance of cross talk among redox, Ca(2+), and protein homeostasis in the ER.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Dnajc10 recombinant protein

 Products by Pathway  Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram

Diseases associated with Dnajc10 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with Dnajc10 and Neoplasms
 Adenocarcinoma Antibodies  >1 publications with Dnajc10 and Adenocarcinoma
 Liver Neoplasms Antibodies  >1 publications with Dnajc10 and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with Dnajc10 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with Dnajc10 and Carcinoma, Hepatocellular

Organs/Tissues associated with Dnajc10 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Thymus Antibodies  >1 publications with Dnajc10 and Thymus
 Salivary Gland Antibodies  >1 publications with Dnajc10 and Salivary Gland
 Testis Antibodies  >1 publications with Dnajc10 and Testis
 Liver Antibodies  >1 publications with Dnajc10 and Liver
 Kidney Antibodies  >1 publications with Dnajc10 and Kidney
 Pancreas Antibodies  >1 publications with Dnajc10 and Pancreas
 Lung Antibodies  >1 publications with Dnajc10 and Lung
 Brain Antibodies  >1 publications with Dnajc10 and Brain
 Embryonic Tissue Antibodies  >1 publications with Dnajc10 and Embryonic Tissue
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