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Transcription Elongation Factor A (TCEAL1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143060

Description: TCEAL1 Human Recombinant fused with an 8 amino acid His tag at C-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 167 amino acids (1-159 a.a.) and having a molecular mass of 19.7kDa. The TCEAL1 is purified… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Transcription Elongation Factor A (TCEAL1), Recombinant Protein
Full Product Name
Recombinant Human Transcription Elongation Factor A (SII)-Like 1
Product Synonym Names
TCEAL1 Human; Transcription Elongation Factor A (SII)-Like 1 Human Recombinant; Transcription elongation factor A protein-like 1; TCEA-like protein 1; Nuclear phosphoprotein p21/SIIR; Transcription elongation factor S-II protein-like 1; TCEAL1; SIIR; p21; pp21
Sequence
MDKPRKENEE EPQSAPKTDE ERPPVEHSPE KQSPEEQSSE EQSSEEEFFP EELLPELLPE MLLSEERPPQ EGLSRKDLFE GRPPMEQPPC GVGKHKLEEG SFKERLARSR PQFRGDIHGR NLSNEEMIQA ADELEEMKRV RNKLMIMHWK AKRSRPYPI< u>L EHHHHHH.
Host
E Coli
Form/Format
The TCEAL1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 20% glycerol and 0.1M NaCl.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Molecular Weight
18,641 Da
OMIM
300237
3D Structure
ModBase 3D Structure for Q15170

Other Notes

Small volumes of TCEAL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TCEAL1 purchase

MBS143060 is a recombinant protein targeting TCEAL1. Also known as Recombinant Human Transcription Elongation Factor A (SII)-Like 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TCEAL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transcription elongation factor A protein-like 1
NCBI Official Synonym Full Names
transcription elongation factor A (SII)-like 1
NCBI Official Symbol
TCEAL1
NCBI Official Synonym Symbols
p21; SIIR; WEX9; pp21
UniProt Protein Name
Transcription elongation factor A protein-like 1
UniProt Synonym Protein Names
Nuclear phosphoprotein p21/SIIR; Transcription elongation factor S-II protein-like 1
UniProt Gene Name
TCEAL1
UniProt Synonym Gene Names
SIIR; TCEA-like protein 1
UniProt Entry Name
TCAL1_HUMAN
NCBI Protein Information
transcription elongation factor A protein-like 1; TCEA-like protein 1; nuclear phosphoprotein p21/SIIR; transcription elongation factor S-II protein-like 1

NCBI Summary for TCEAL1

This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
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UniProt Comments for TCEAL1

SIIR: May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context- dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly. Belongs to the TFS-II family. TFA subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: Xq22.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: transcription factor activity

Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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