Bovine TF Native Protein – Cat# MBS143063

Holo Transferrin (TF) Bovine Native Protein

Name: TF Native Protein; Holo Transferrin; Bovine; MyBioSource
Brand: MyBioSource
SKU: MBS143063
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143063

Description: Bovine Holo Transferrin is a glycoprotein of approximately 80 kDa.Introduction: Transferrin is the iron-transport protein of vertebrate serum and donates iron to cells through interaction with a specific membrane receptor, CD71. Transferrin… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Holo Transferrin (TF), Native Protein

Full Product Name

Bovine Holo Transferrin

Product Gene Name

TF native protein

Product Synonym Names

HTF Bovine; Holo Transferrin Bovine; Serotransferrin; Transferrin; Siderophilin; Beta-1-metal-binding globulin; TF; PRO1557; PRO2086; DKFZp781D0156; Holo Transferrin; HTF; bHolo Transferrin

Form/Format

The protein (1mg/ml) was lyophilized with no additives.
Sterile Filtered Pink lyophilized (freeze-dried) powder.

Purity/Purification

Greater than 97.0% as determined by Cellulose Acetate.

Preparation and Storage

Lyophilized Bovine HTF although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Bovine HTF should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.

Molecular Weight

77,753 Da

3D Structure

ModBase 3D Structure for Q29443

Virus Test

FDA approved Plasma from each donor has been tested and found negative for antibody to HIV-1, HIV-2, HCV, HBSAG, HBc, ALT and Syphilis.Viral inactivation by pasteurization (60 degree C for 10 hours) has been validated using three different test viruses, with removal of 8-14.5 logs of virus documented. The purification process has also been found to remove significant additional quantities of virus.

Solubility

It is recommended to reconstitute the lyophilized Bovine HTF in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Product Categories/Family for TF native protein

Recombinant & Natural Proteins; Natural Proteins; Transferrin

Application Notes for TF native protein

Bovine Transferrin is a crucial component for the cultivation of mammalian cells in-vitro. Bovine Transferrin is Critical for long-term cells growth in-vitro. Bovine Transferrin is used as detoxificant in media by binding contaminating metal ions. Bovine Transferrin is often used as a nutrient in fermentation media for recombinant protein and biopharmaceutical production. Additional common uses of Bovine Transferrin areMolecular weight, Affinity purification of anti-human transferrin antibodies and also as receptor mediated transfection of molecules such as DNA, into cells.

Other Notes

Small volumes of TF native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TF purchase

MBS143063 is a native protein targeting TF. Also known as Bovine Holo Transferrin.

Additional Details

NCBI/Uniprot data below describe general gene information for TF. It may not necessarily be applicable to this product.

NCBI GI #

114326282

NCBI GeneID

280705

NCBI Accession #

NP_803450.2

UniProt Primary Accession #

Q29443

UniProt Secondary Accession #

Q0IIK2

UniProt Related Accession #

Q29443

GenBank Nucleotide #

NM_177484.3

NCBI Official Full Name

serotransferrin

NCBI Official Synonym Full Names

transferrin<

NCBI Official Symbol

UniProt Protein Name

Serotransferrin

UniProt Synonym Protein Names

Beta-1 metal-binding globulin; Siderophilin

UniProt Gene Name

UniProt Synonym Gene Names

Transferrin

UniProt Entry Name

TRFE_BOVIN

NCBI Protein Information

serotransferrin; beta-1 metal-binding globulin; siderophilin

UniProt Comments for TF

Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

Research Articles on TF

1. The TF gene has an effect on milk fat yield.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TF native protein

Products by Pathway	Pathway Diagram
HIF-1 Signaling Pathway antibodies	HIF-1 Signaling Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Iron Uptake And Transport Pathway antibodies	Iron Uptake And Transport Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram
Mineral Absorption Pathway antibodies	Mineral Absorption Pathway Diagram
Platelet Activation, Signaling And Aggregation Pathway antibodies	Platelet Activation, Signaling And Aggregation Pathway Diagram
Platelet Degranulation Pathway antibodies	Platelet Degranulation Pathway Diagram
Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies	Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
Transferrin Endocytosis And Recycling Pathway antibodies	Transferrin Endocytosis And Recycling Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram

Diseases associated with TF native protein

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>1489 publications with TF and Cardiovascular Diseases
Inflammation Antibodies	>815 publications with TF and Inflammation
Heart Diseases Antibodies	>601 publications with TF and Heart Diseases
Carcinoma Antibodies	>535 publications with TF and Carcinoma
Necrosis Antibodies	>510 publications with TF and Necrosis
Immune System Diseases Antibodies	>434 publications with TF and Immune System Diseases
Atherosclerosis Antibodies	>289 publications with TF and Atherosclerosis
Liver Diseases Antibodies	>251 publications with TF and Liver Diseases
Breast Neoplasms Antibodies	>229 publications with TF and Breast Neoplasms
Lung Neoplasms Antibodies	>180 publications with TF and Lung Neoplasms

Organs/Tissues associated with TF native protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>964 publications with TF and Brain
Liver Antibodies	>631 publications with TF and Liver
Lung Antibodies	>485 publications with TF and Lung
Kidney Antibodies	>447 publications with TF and Kidney
Embryonic Tissue Antibodies	>383 publications with TF and Embryonic Tissue
Skin Antibodies	>212 publications with TF and Skin
Intestine Antibodies	>114 publications with TF and Intestine
Ovary Antibodies	>89 publications with TF and Ovary
Testis Antibodies	>88 publications with TF and Testis
Adipose Tissue Antibodies	>78 publications with TF and Adipose Tissue