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Regulator of G-Protein Signaling 7-Binding Protein (RGS7BP) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1430643

MBS1430643 is a recombinant protein targeting RGS7BP. Also known as Recombinant Human Regulator of G-protein signaling 7-binding protein (RGS7BP). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$940 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Regulator of G-protein signaling 7-binding protein (RGS7BP), Recombinant Protein
Full Product Name
Recombinant Human Regulator of G-protein signaling 7-binding protein (RGS7BP)
Product Gene Name
RGS7BP recombinant protein
Product Synonym Gene Name
RGS7BP
Sequence
MSSAPNGRKK RPSRSTRSSI FQISKPPLQS GDWERRGSGS ESAHKTQRAL DDCKMLVQEF NTQVALYREL VISIGDVSVS CPSLRAEMHK TRTKGCEMAR QAHQKLAAIS GPEDGEIHPE ICRLYIQLQC CLEMYTTEML KSICLLGSLQ FHRKGKEPGG GTKSLDCKIE ESAETPALED SSSSPVDSQQ HSWQVSTDIE NTERDMREMK NLLSKLRETM PLPLKNQDDS SLLNLTPYPL VRRRKRRFFG LCCLISS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
28,962 Da
Sequence Positions
1-257, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
610890
3D Structure
ModBase 3D Structure for Q6MZT1
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RGS7BP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RGS7BP. It may not necessarily be applicable to this product.

NCBI GI #
71274166
NCBI GeneID
401190
NCBI Accession #
NP_001025046.1
UniProt Primary Accession #
Q6MZT1
UniProt Secondary Accession #
B7Z3X1
UniProt Related Accession #
Q6MZT1
GenBank Nucleotide #
NM_001029875.2
NCBI Official Full Name
regulator of G-protein signaling 7-binding protein isoform 1
NCBI Official Synonym Full Names
regulator of G protein signaling 7 binding protein
NCBI Official Symbol
RGS7BP
NCBI Official Synonym Symbols
R7BP
UniProt Protein Name
Regulator of G-protein signaling 7-binding protein
UniProt Synonym Protein Names
R7 family-binding protein
Protein Family
Regulator of G-protein signaling 7-binding protein
UniProt Gene Name
RGS7BP
UniProt Synonym Gene Names
R7BP
NCBI Protein Information
regulator of G-protein signaling 7-binding protein

NCBI Summary for RGS7BP

This gene encodes a protein that binds to all members of the R7 subfamily of regulators of G protein signaling and regulates their translocation between the nucleus and the plasma membrane. The encoded protein could be regulated by reversible palmitoylation, which anchors it to the plasma membrane. Depalmitoylation localizes the protein to the nucleus. Polymorphisms in this gene may be associated with risk of aspirin-exacerbated respiratory disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]
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UniProt Comments for RGS7BP

Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cypolasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
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Research Articles on RGS7BP

1. Data (including data from studies using transgenic mice) suggest that R7BP-RGS7 heterotrimers interact with Galpha13 to augment signaling pathways in neurons that regulate neurite morphogenesis. (R7BP = RGS7 family binding protein; RGS7 = regulator of G-protein signaling 7 protein; Galpha13 = GTP-binding protein alpha subunit 13)
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with RGS7BP recombinant protein

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with RGS7BP and Liver Diseases
 Kidney Diseases Antibodies  >1 publications with RGS7BP and Kidney Diseases

Organs/Tissues associated with RGS7BP recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with RGS7BP and Kidney
 Brain Antibodies  >1 publications with RGS7BP and Brain
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