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Synaptobrevin-1 (VAMP1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143127

Description: VAMP1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 111 amino acids and having a molecular mass of 11.9 kDa.Introduction: Synaptobrevin 1(Vehicle-associated membrane, VAMP1) is one of the key… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Synaptobrevin-1 (VAMP1), Recombinant Protein
Full Product Name
Recombinant Human Synaptobrevin-1
Product Gene Name
Product Synonym Names
VAMP1 Human; Synaptobrevin-1 Human Recombinant; Vesicle-associated membrane protein 1; SYB1; VAMP-1; Synaptobrevin-1; VAMP1; DKFZp686H12131
Sequence
MGSSHHHHHH SSGLVPRGSH MSAPAQPPAE GTEGTAPGGG PPGPPPNMTS NRRLQQTQAQ VEEVVDIIRV NVDKVLERDQ KLSELDDRAD ALQAGASQFE SSAAKLKRKY W
Host
E Coli
Form/Format
The protein solution (1mg/ml) contains 1X PBS and 1mM EDTA.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Molecular Weight
12,658 Da
OMIM
108600
3D Structure
ModBase 3D Structure for P23763

Other Notes

Small volumes of VAMP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VAMP1 purchase

MBS143127 is a recombinant protein targeting VAMP1. Also known as Recombinant Human Synaptobrevin-1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for VAMP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
vesicle-associated membrane protein 1 isoform 4
NCBI Official Synonym Full Names
vesicle-associated membrane protein 1 (synaptobrevin 1)
NCBI Official Symbol
VAMP1
NCBI Official Synonym Symbols
SYB1; SPAX1; VAMP-1
UniProt Protein Name
Vesicle-associated membrane protein 1
UniProt Synonym Protein Names
Synaptobrevin-1
UniProt Gene Name
VAMP1
UniProt Synonym Gene Names
SYB1; VAMP-1
UniProt Entry Name
VAMP1_HUMAN
NCBI Protein Information
vesicle-associated membrane protein 1; synaptobrevin 1; synaptobrevin-1

NCBI Summary for VAMP1

Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]
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UniProt Comments for VAMP1

VAMP1: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p

Cellular Component: SNARE complex; synaptic vesicle; mitochondrial outer membrane; neuron projection; cell surface; synaptic vesicle membrane; integral to plasma membrane; cell junction; cytosol

Molecular Function: SNAP receptor activity; SNARE binding; protein binding

Biological Process: vesicle fusion; exocytosis; pathogenesis

Disease: Spastic Ataxia 1, Autosomal Dominant
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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