Human DHDH Recombinant Protein – Cat# MBS1432652

Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase (DHDH) Human Recombinant Protein

Name: DHDH Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1432652
Price: 455 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1432652

MBS1432652 is a recombinant protein targeting DHDH. Also known as Recombinant Human Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (DHDH). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$455 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (DHDH), Recombinant Protein

Full Product Name

Recombinant Human Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (DHDH)

Product Gene Name

DHDH recombinant protein

Product Synonym Gene Name

DHDH; 2DD

Product Synonym Names

Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; EC=1.3.1.20; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; EC=1.1.1.179; Dimeric dihydrodiol dehydrogenase; Hum2DD

Sequence

MALRWGIVSV GLISSDFTAV LQTLPRSEHQ VVAVAARDLS RAKEFAQKHD IPKAYGSYEE LAKDPSVEVA YIGTQHPQHK AAVMLCLAAG KAVLCEKPTG VNAAEVREMV AEARSRALFL MEAIWTRFFP ASEALRSVLA QGTLGDLRVA RAEFGKNLIH VPRAVDRAQA GGALLDIGIY CVQFTSMVFG GQKPEKISVV GRRHETGVDD TVTVLLQYPG EVHGSFTCSI TVQLSNTASV SGTKGMVQLL NPCWCPTELV VKGEHKEFPL PPVPKDCNFD NGAGMSYEAK HVWECLRKGM KESPVIPLSE SELLADILEE VRKAIGVTFP QDKR

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

63.4 kDa

Sequence Positions

1-334aa; Full Length

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

606377

3D Structure

ModBase 3D Structure for Q9UQ10

Species

Homo sapiens (Human)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DHDH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DHDH. It may not necessarily be applicable to this product.

NCBI GI #

7657212

NCBI GeneID

27294

NCBI Accession #

NP_055290.1

UniProt Primary Accession #

Q9UQ10

UniProt Related Accession #

Q9UQ10

GenBank Nucleotide #

NM_014475.3

NCBI Official Full Name

trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

NCBI Official Synonym Full Names

dihydrodiol dehydrogenase (dimeric)

NCBI Official Symbol

DHDH

NCBI Official Synonym Symbols

2DD; HUM2DD

UniProt Protein Name

Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

UniProt Synonym Protein Names

D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase (EC:1.1.1.179); Dimeric dihydrodiol dehydrogenase; Hum2DD

Protein Family

Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

UniProt Gene Name

DHDH

UniProt Synonym Gene Names

2DD

UniProt Entry Name

DHDH_HUMAN

NCBI Protein Information

trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; 3-deoxyglucosone reductase; D-xylose-NADP dehydrogenase

NCBI Summary for DHDH

This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008]

UniProt Comments for DHDH

DHDH: an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008]

Protein type: EC 1.3.1.20; EC 1.1.1.179; Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase

Chromosomal Location of Human Ortholog: 19q13.3

Molecular Function: NAD(P) transhydrogenase activity; electron carrier activity; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; D-xylose 1-dehydrogenase (NADP+) activity

Biological Process: carbohydrate metabolic process; D-xylose catabolic process

Research Articles on DHDH

1. Some genetical studies show also altered expression of the dehydrogenases ALDH2 and DHDH genes in patients with Dupuytren's disease and with digestive tract malignancies related to alcohol abuse.(review)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DHDH recombinant protein

Products by Pathway	Pathway Diagram
Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies	Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies	Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
Pentose And Glucuronate Interconversions Pathway antibodies	Pentose And Glucuronate Interconversions Pathway Diagram
Pentose And Glucuronate Interconversions Pathway antibodies	Pentose And Glucuronate Interconversions Pathway Diagram

Diseases associated with DHDH recombinant protein

Disease Name	Pubmed Publications
Eye Diseases Antibodies	>1 publications with DHDH and Eye Diseases
Bone Diseases Antibodies	>1 publications with DHDH and Bone Diseases
Nervous System Diseases Antibodies	>1 publications with DHDH and Nervous System Diseases

Organs/Tissues associated with DHDH recombinant protein

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with DHDH and Bone