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Trefoil Factor-2 (TFF2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143345

Description: TFF-2 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 116 amino acids (24-129) which includes a 10 amino acid His Tag fused at N-terminus and having a total molecular mass of 13.2 kDa. TFF2 Human… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Trefoil Factor-2 (TFF2), Recombinant Protein
Full Product Name
Recombinant Human Trefoil Factor-2 His Tag
Product Gene Name
Product Synonym Names
TFF2 Human, His; Trefoil Factor-2 Human Recombinant, His Tag; TFF-2; Spasmolytic polypeptide; Spasmolysin; SML1; Trefoil factor 2; SP; TFF2; TFF2 His
Sequence
MKHHHHHHAS EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
Host
E Coli
Form/Format
The TFF2 protein was lyophilized from 0.4um filtered solution at a concentration of 0.5mg/ml containing 20mM Tris pH-7.5, and 20mM NaCl.
Filtered White lyophilized (freeze-dried) powder.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
Lyophilized TFF2 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution TFF2 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Molecular Weight
14,284 Da
OMIM
182590
3D Structure
ModBase 3D Structure for Q03403
Solubility
It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Other Notes

Small volumes of TFF2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TFF2 purchase

MBS143345 is a recombinant protein targeting TFF2. Also known as Recombinant Human Trefoil Factor-2 His Tag. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TFF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
trefoil factor 2
NCBI Official Synonym Full Names
trefoil factor 2
NCBI Official Symbol
TFF2
NCBI Official Synonym Symbols
SP; SML1
UniProt Protein Name
Trefoil factor 2
UniProt Synonym Protein Names
Spasmolysin; Spasmolytic polypeptide; SP
Protein Family
UniProt Gene Name
TFF2
UniProt Synonym Gene Names
SML1; SP
UniProt Entry Name
TFF2_HUMAN
NCBI Protein Information
trefoil factor 2; spasmolysin; spasmolytic polypeptide; spasmolytic protein 1

NCBI Summary for TFF2

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
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UniProt Comments for TFF2

TFF2: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: extracellular space

Molecular Function: protein binding; CXCR4 chemokine receptor binding

Biological Process: negative regulation of inflammatory response; positive regulation of cell proliferation; digestion; calcium-mediated signaling; negative regulation of macrophage activation; regulation of cell migration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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