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Adenylate Kinase 3 Like 1 (AK3L1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143388

Description: AK3L1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 259 amino acids (1-223) and having a molecular mass of 29.3 kDa. The AK3L1 is fused with 35 amino acid His-tag at N-terminus.AK3L1 is purified… More details

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Product Overview

Online Datasheet in PDF
Product Name
Adenylate Kinase 3 Like 1 (AK3L1), Recombinant Protein
Full Product Name
Recombinant Human Adenylate Kinase 3 Like 1
Product Gene Name
Product Synonym Names
AK3L1 Human; Adenylate Kinase-3 Like 1 Human Recombinant; AK3; Adenylate kinase 3 alpha like 1; AK3L1; AK4
Sequence
MRGSHHH HHH GMASMTGGQQ MGRDLYDDDD KDRWGS MASK LLRAVILGPP GSGKGTVSQR IAQNFGLQHL SSGHFLRENI KASTEVGEMA KQYIEKSLLV PDHVITRLMM SELENRRGQH WLLDGFPRTL GQAEALDKIC EVDLVISLNI PFETLKDRLS RRWIHPPSGR VYNLDFNPPH VHGIDDVTGE PLVQQEDDKP EAVAARLRQY KDVAKPVIEL YKSRGVLHQF SGTETNKIWP YVYTLFSNKI TPIQSKEAY
Host
E Coli
Form/Format
AK3L1 solution containing 20mM Tris pH-8, 2mM DTT and 20% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Preparation and Storage
AK3L1 Human Recombinant although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
Molecular Weight
25,268 Da
OMIM
103030
3D Structure
ModBase 3D Structure for Q6IBH4

Other Notes

Small volumes of AK3L1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AK3L1 purchase

MBS143388 is a recombinant protein targeting AK3L1. Also known as Recombinant Human Adenylate Kinase 3 Like 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for AK3L1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
adenylate kinase 4, mitochondrial
NCBI Official Synonym Full Names
adenylate kinase 4
NCBI Official Symbol
AK4
NCBI Official Synonym Symbols
AK3; AK 4; AK3L1; AK3L2
UniProt Protein Name
Adenylate kinase 4, mitochondrial
UniProt Synonym Protein Names
Adenylate kinase 3-like; GTP:AMP phosphotransferase AK4
UniProt Gene Name
AK4
UniProt Entry Name
KAD4_HUMAN
NCBI Protein Information
adenylate kinase 4, mitochondrial; AK 4; AK4; ATP-AMP transphosphorylase; GTP:AMP phosphotransferase AK4, mitochondrial; adenylate kinase 3-like 1; adenylate kinase isoenzyme 4, mitochondrial; mitochondrial adenylate kinase-3; nucleoside-triphosphate-adenylate kinase

NCBI Summary for AK3L1

This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq, Jul 2008]
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UniProt Comments for AK3L1

AK3L1: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. May also be active with GTP. Belongs to the adenylate kinase family.

Protein type: Mitochondrial; Kinase, other; EC 2.7.4.6; EC 2.7.4.10; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: mitochondrion; mitochondrial matrix

Molecular Function: GTP binding; nucleoside diphosphate kinase activity; adenylate kinase activity; nucleoside triphosphate adenylate kinase activity; ATP binding

Biological Process: response to drug; ATP metabolic process; nucleoside triphosphate biosynthetic process; nucleoside diphosphate phosphorylation; ADP biosynthetic process; brain development; AMP metabolic process; liver development; GTP metabolic process
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Research Articles on AK3L1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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