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DNA-Binding Protein BIN4 (BIN4) Arabidopsis Thaliana Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1434760

MBS1434760 is a recombinant protein targeting BIN4. Also known as Recombinant Arabidopsis thaliana DNA-binding protein BIN4 (BIN4). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1230 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNA-binding protein BIN4 (BIN4), Recombinant Protein
Full Product Name
Recombinant Arabidopsis thaliana DNA-binding protein BIN4 (BIN4)
Product Gene Name
BIN4 recombinant protein
Product Synonym Gene Name
BIN4
Sequence
MSSSSREGSP DWLRSYEAPM TTSLLSLSSS DDDSPYRESE VISSLPLPDD DGDDIVVLET ESVELLTRKN SETKVVTKQV SIEQVFSRKK KADASLNLED SCAGKENGNN VDCEKLSSKH KDAQGGADSV WLVSSDSEPS SPIKQEVTVS TEKDADFVLE ATEEEPAVKT VRKEKSPKTK SKSSRKTPKE GNSAQEILKT EDKDTDTTIA EQVTPEKSPK TKSKSSRKTP KEENCAQEIL KTEDKDKDTD TDTIIAEEVT TDQKIKPSSG SSSRLPLVLS EKVNRTKVLV ECEGDSIDLS GDMGAVGRVV VSDTTGDMYL DLKGTIYKST IIPSRTFCVV NVGQTEAKIE AIMNDFIQLI PQSNVYEAET MVEGTLEGFT FESDDESNKN AKTAVKPADQ SVGTEEETNT KAKPKAKAKG ETVIGKKRGR PSKEKQPPAK KARNSAPKKP KAKK
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
49,485 Da
Sequence Positions
1-454, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q9FLU1
Species
Arabidopsis thaliana (Mouse-ear cress)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of BIN4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BIN4. It may not necessarily be applicable to this product.

NCBI GI #
238481373
NCBI GeneID
832534
NCBI Accession #
NP_001154739.1
UniProt Primary Accession #
Q9FLU1
UniProt Related Accession #
Q9FLU1
GenBank Nucleotide #
NM_001161267.1
NCBI Official Full Name
double-stranded DNA binding protein
NCBI Official Symbol
BIN4
NCBI Official Synonym Symbols
brassinosteroid-insensitive4; K18P6.17; K18P6_17; MID; MIDGET
UniProt Protein Name
DNA-binding protein BIN4
UniProt Synonym Protein Names
Protein BRASSINOSTEROID INSENSITIVE 4; Protein MIDGET
Protein Family
DNA-binding protein
UniProt Gene Name
BIN4
UniProt Synonym Gene Names
MID
NCBI Protein Information
double-stranded DNA binding protein

NCBI Summary for BIN4

This gene is predicted to encode a protein that forms part of the topoisomerase VI complex. BIN4 is a nuclear-localized protein that can bind DNA. bin4 mutants are brassinolide-insensitive dwarves with severely reduced cell size in leaves, roots, and hypocotyls. Proper development of root hairs and trichomes is also disrupted in bin4 mutants and they have elevated levels of double strand breaks in their cotyledon cells.
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UniProt Comments for BIN4

Component of the DNA topoisomerase VI complex. Binds to DNA. Required for chromatin organization and progression of endoreduplication cycles. The loss of BIN4 activates the ATM- and ATR-dependent DNA damage responses in postmitotic cells and induces the ectopic expression of the mitotic G2/M-specific cyclin B1;1 gene in non-dividing cells.
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Research Articles on BIN4

1. The MID protein plays a role in COP1/SPA1-controlled repression of flowering under short-day conditions. [MIDGET] [MID]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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