Human PPIG Active Protein – Cat# MBS143499

Cyclophilin-G (PPIG) Human Active Protein

Name: PPIG Active Protein; Cyclophilin-G; Human; MyBioSource
Brand: MyBioSource
SKU: MBS143499
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143499

Description: Cyclophilin-G Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 195amino acids (1-175 a.a.) and having a molecular mass of 21.6 kDa. Cyclophilin-G is fused to a 20 amino acid His Tag at N-terminus… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cyclophilin-G (PPIG), Active Protein

Full Product Name

Recombinant Human Cyclophilin-G

Product Gene Name

PPIG active protein

Product Synonym Names

Cyclophilin G Human; Cyclophilin-G Human Recombinant; Peptidyl-prolyl cis-trans isomerase G; PPIase G; Rotamase G; PPIG; peptidylprolyl isomerase G; Cyclophilin G; Peptidyl-prolyl isomerase G; Rotamase G; Clk-associating RS-cyclophilin; CARS-cyclophilin; CARS-Cyp; SR-cyclophilin; SR-cyp; SRcyp; CASP10; CYP; MGC133241; Cyclophilin G

Sequence

MGSSHHH HHH SSGLVPRGSH MGIKVQRPRC FFDIAINNQP AGRVVFELFS DVCPKTCENF RCLCTGEKGT GKSTQKPLHY KSCLFHRVVK DFMVQGGDFS EGNGRGGESI YGGFFEDESF AVKHNKEFLL SMANRGKDTN GSQFFITTKP TPHLDGHHVV FGQVISGQEV VREIENQKTD AASKPFAEVR ILSCG

Host

E Coli

Form/Format

Cyclophilin-G solution containing 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol.
Sterile filtered colorless solution.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Molecular Weight

40,299 Da

OMIM

606093

3D Structure

ModBase 3D Structure for Q13427

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Specific activity is > 200 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 25C in Tris-Hcl pH8.0 using chymotrypsin.

Product Categories/Family for PPIG active protein

Enzymes; Cyclophilin

Other Notes

Small volumes of PPIG active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPIG purchase

MBS143499 is an active protein targeting PPIG. Also known as Recombinant Human Cyclophilin-G. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PPIG. It may not necessarily be applicable to this product.

NCBI GI #

42560244

NCBI GeneID

9360

NCBI Accession #

NP_004783.2

UniProt Primary Accession #

Q13427

UniProt Secondary Accession #

O00706; Q53R40; Q53SN4; Q96DG9; D3DPC5; D3DPC6

UniProt Related Accession #

Q13427

GenBank Nucleotide #

NM_004792.2

NCBI Official Full Name

peptidyl-prolyl cis-trans isomerase G

NCBI Official Synonym Full Names

peptidylprolyl isomerase G (cyclophilin G)

NCBI Official Symbol

PPIG

NCBI Official Synonym Symbols

CYP; SRCyp; SCAF10; CARS-Cyp

UniProt Protein Name

Peptidyl-prolyl cis-trans isomerase G

UniProt Synonym Protein Names

CASP10; Clk-associating RS-cyclophilin; CARS-Cyp; CARS-cyclophilin; SR-cyclophilin; SR-cyp; SRcyp; Cyclophilin G; Rotamase G

Protein Family

Peptidyl-prolyl cis-trans isomerase

UniProt Gene Name

PPIG

UniProt Synonym Gene Names

PPIase G; Peptidyl-prolyl isomerase G; CARS-Cyp; CARS-cyclophilin; SR-cyclophilin; SR-cyp; SRcyp

UniProt Entry Name

PPIG_HUMAN

NCBI Protein Information

peptidyl-prolyl cis-trans isomerase G; CARS-cyclophilin; CASP10; Clk-associating RS-cyclophilin; PPIase G; SR-cyclophilin; SR-cyp; SR-related CTD-associated factor 10; cyclophilin G; peptidyl-prolyl isomerase G (cyclophilin G); rotamase G

UniProt Comments for PPIG

PPIG: an ubiquitous peptidyl-prolyl cis/trans isomerase. Distributed in nuclear speckles, which are rich in splicing factors. Colocalizes with the splicing factor SFRS2. A component of splicing factor complexes that bind the phosphorylated C-terminal domain (CTD) of RNA polymerase II. Interacts with CLK1 and PNN. Two splice variant isoforms of the human protein have been described.

Protein type: EC 5.2.1.8; Isomerase; Cyclophilin

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: nucleoplasm; nuclear matrix; cytoplasm; nuclear speck; nucleus

Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity; cyclosporin A binding

Biological Process: protein peptidyl-prolyl isomerization; protein folding; RNA splicing

Research Articles on PPIG

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PPIG active protein

Reference Product	PubMed Publications
CYP2C19 active protein	>1 publications with PPIG and CYP2C19
CYP3A4 active protein	>1 publications with PPIG and CYP3A4
PNN active protein	>1 publications with PPIG and PNN

Diseases associated with PPIG active protein

Disease Name	Pubmed Publications
Drug-Related Side Effects and Adverse Reactions Antibodies	>1 publications with PPIG and Drug-Related Side Effects and Adverse Reactions
Heart Defects, Congenital Antibodies	>1 publications with PPIG and Heart Defects, Congenital

Organs/Tissues associated with PPIG active protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with PPIG and Blood
Skin Antibodies	>2 publications with PPIG and Skin
Ear Antibodies	>1 publications with PPIG and Ear
Liver Antibodies	>1 publications with PPIG and Liver