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WNT Inhibitory Factor 1 (WIF1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143513

Description: WIF1 produced in Hi-5 cells is a single, glycosylated polypeptide chain containing 369 amino acids (29-379 a.a.) and having a molecular mass of 40.5 kDa, (48kDa on SDS-PAGE). WIF1 is fused to 16 amino acid His Tag at C-Terminus and purified by… More details

$285 / 0.002 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WNT Inhibitory Factor 1 (WIF1), Recombinant Protein
Full Product Name
Recombinant Human WNT Inhibitory Factor 1
Product Gene Name
Product Synonym Names
WIF1 Human; WNT Inhibitory Factor 1 Human Recombinant; WIF1; WIF-1; Wnt inhibitory factor 1
Sequence
ADL GPPQEES LYLWIDAHQA RVLIGFEEDI LIVSEGKMAP FTHDFRKAQQ RMPAIPVNIH SMNFTWQAAG QAEYFYEFLS LRSLDKGIMA DPTVNVPLLG TVPHKASVVQ VGFPCLGKQD GVAAFEVDVI VMNSEGNTIL KTPQNAIFFK TCQQAECPGG CRNGGFCNER RICECPDGFH GPHCEKALCT PRCMNGGLCV TPGFCICPPG FYGVNCDKAN CSTTCFNGGT CFYPGKCICP PGLEGEQCEI SKCPQPCRNG GKCIGKSKCK CSKGYQGDLC SKPVCEPGCG AHGTCHEPNK CQCQEGWHGR HCNKRYEASL IHALRPAGAQ LRQHTPSLKK AEERRDPPES NYIW SGRLVP RGSHHHHHH
Host
Hi-5 Cells
Form/Format
The WIF1 protein solution contains 1X PBS pH 7.4, 10% glycerol and 1mM PMSF.
Sterile filtered colorless solution.
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
OMIM
605186
3D Structure
ModBase 3D Structure for Q9Y5W5

Other Notes

Small volumes of WIF1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WIF1 purchase

MBS143513 is a recombinant protein targeting WIF1. Also known as Recombinant Human WNT Inhibitory Factor 1. Host: Hi-5 Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for WIF1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
wnt inhibitory factor 1
NCBI Official Synonym Full Names
WNT inhibitory factor 1
NCBI Official Symbol
WIF1
NCBI Official Synonym Symbols
WIF-1
UniProt Protein Name
Wnt inhibitory factor 1
Protein Family
UniProt Gene Name
WIF1
UniProt Synonym Gene Names
WIF-1
UniProt Entry Name
WIF1_HUMAN
NCBI Protein Information
wnt inhibitory factor 1

NCBI Summary for WIF1

The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]
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UniProt Comments for WIF1

WIF1: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.

Protein type: Secreted, signal peptide; Secreted; Inhibitor

Chromosomal Location of Human Ortholog: 12q14.3

Cellular Component: extracellular region

Molecular Function: protein binding

Biological Process: Wnt receptor signaling pathway; multicellular organismal development; positive regulation of fat cell differentiation; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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