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Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-Beta (PPARGC1B) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1435211

MBS1435211 is a recombinant protein targeting Ppargc1b. Also known as Recombinant Rat Peroxisome proliferator-activated receptor gamma coactivator 1-beta (Ppargc1b) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Peroxisome proliferator-activated receptor gamma coactivator 1-beta (Ppargc1b), Recombinant Protein
Full Product Name
Recombinant Rat Peroxisome proliferator-activated receptor gamma coactivator 1-beta (Ppargc1b) , partial
Product Gene Name
Ppargc1b recombinant protein
Product Synonym Gene Name
Ppargc1b
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
109,383 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q811R2
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Ppargc1b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ppargc1b. It may not necessarily be applicable to this product.

NCBI GI #
28570176
NCBI GeneID
291567
NCBI Accession #
NP_788264.1
UniProt Primary Accession #
Q811R2
UniProt Related Accession #
Q811R2
GenBank Nucleotide #
NM_176075.2
NCBI Official Full Name
peroxisome proliferator-activated receptor gamma coactivator 1-beta
NCBI Official Synonym Full Names
PPARG coactivator 1 beta
NCBI Official Symbol
Ppargc1b
NCBI Official Synonym Symbols
Perc; PGC1beta
UniProt Protein Name
Peroxisome proliferator-activated receptor gamma coactivator 1-beta
Protein Family
Peroxisome proliferator-activated receptor gamma coactivator
UniProt Gene Name
Ppargc1b
UniProt Synonym Gene Names
Perc; Pgc1; Pgc1b; Ppargc1; PGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta
NCBI Protein Information
peroxisome proliferator-activated receptor gamma coactivator 1-beta

UniProt Comments for Ppargc1b

Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be part of the pathways regulating the elevation of gluconeogenesis, beta-oxidation of fatty acids and ketogenesis during fasting. Stimulates SREBP-mediated lipogenic gene expression in the liver. Induces energy expenditure and antagonizes obesity when overexpressed. Induces also the expression of mitochondrial genes involved in oxidative metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
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Research Articles on Ppargc1b

1. Abeta increases the expression of mTOR and p-mTOR at the site of Ser2448, and the stimulation of Abeta is likely to depend on sirtuin 1, PPARgamma, and PGC-1beta pathway in regulating mTOR expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Ppargc1b recombinant protein

 Reference Product  PubMed Publications
 Nrf1 recombinant protein  >8 publications with Ppargc1b and Nrf1
 Tfam recombinant protein  >7 publications with Ppargc1b and Tfam
 Ppara recombinant protein  >4 publications with Ppargc1b and Ppara
 Gabpa recombinant protein  >3 publications with Ppargc1b and Gabpa
 Esrrg recombinant protein  >3 publications with Ppargc1b and Esrrg
 Tfb1m recombinant protein  >2 publications with Ppargc1b and Tfb1m
 Esrrb recombinant protein  >2 publications with Ppargc1b and Esrrb
 Esr1 recombinant protein  >1 publications with Ppargc1b and Esr1

Pathways associated with Ppargc1b recombinant protein

 Products by Pathway  Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Mitochondrial Gene Expression Pathway antibodies  Mitochondrial Gene Expression Pathway Diagram
 Mitochondrial Biogenesis Pathway antibodies  Mitochondrial Biogenesis Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 Transcriptional Activation Of Mitochondrial Biogenesis Pathway antibodies  Transcriptional Activation Of Mitochondrial Biogenesis Pathway Diagram

Diseases associated with Ppargc1b recombinant protein

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >9 publications with Ppargc1b and Breast Neoplasms

Organs/Tissues associated with Ppargc1b recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >9 publications with Ppargc1b and Heart
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