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Eukaryotic Translation Initiation Factor 2a (EIF2A) ELISA Kit for Hamster

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS014355

MBS014355 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Eukaryotic Translation Initiation Factor 2A (EIF2A) ELISA Kit target analytes in biological samples. The concentration gradients… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Eukaryotic Translation Initiation Factor 2A (EIF2A), ELISA Kit
Full Product Name
Hamster Eukaryotic Translation Initiation Factor 2A ELISA Kit
Product Gene Name
EIF2A elisa kit
Species Reactivity
Hamster
Assay Type
Sandwich
Preparation and Storage
Store all reagents at 2-8 degree C
Molecular Weight
64,990 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (150264574..150303803). Location: 3q25.1
OMIM
609234
3D Structure
ModBase 3D Structure for Q9BY44

Other Notes

Small volumes of EIF2A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF2A. It may not necessarily be applicable to this product.

NCBI GI #
54873624
NCBI GeneID
83939
NCBI Accession #
NP_114414.2
UniProt Primary Accession #
Q9BY44
UniProt Secondary Accession #
Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81; A8MPS6; D3DNI9
UniProt Related Accession #
Q9BY44
GenBank Nucleotide #
NM_032025.3
NCBI Official Full Name
eukaryotic translation initiation factor 2A
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 2A, 65kDa
NCBI Official Symbol
EIF2A
NCBI Official Synonym Symbols
CDA02; EIF-2A; MST089; MSTP004; MSTP089
UniProt Protein Name
Eukaryotic translation initiation factor 2A
UniProt Synonym Protein Names
65 kDa eukaryotic translation initiation factor 2A
Protein Family
Eukaryotic translation initiation factor
UniProt Gene Name
EIF2A
UniProt Synonym Gene Names
eIF-2A
UniProt Entry Name
EIF2A_HUMAN
NCBI Protein Information
eukaryotic translation initiation factor 2A; 65 kDa eukaryotic translation initiation factor 2A

NCBI Summary for EIF2A

EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002 [PubMed 12133843]).[supplied by OMIM, Mar 2008]

UniProt Comments for EIF2A

EIF2A: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins. Belongs to the WD repeat EIF2A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Translation

Chromosomal Location of Human Ortholog: 3q25.1

Cellular Component: extracellular space; cytoplasm; eukaryotic translation initiation factor 2 complex

Molecular Function: protein binding; translation initiation factor activity; ribosome binding; tRNA binding

Biological Process: regulation of translation; positive regulation of signal transduction; ribosome assembly; translational initiation; SREBP-mediated signaling pathway; protein amino acid phosphorylation
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Research Articles on EIF2A

1. PERK/eIF2alpha signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EIF2A elisa kit

 Reference Product  PubMed Publications
 EIF5B elisa kit  >1 publications with EIF2A and EIF5B

Pathways associated with EIF2A elisa kit

 Products by Pathway  Pathway Diagram
 IL-6 Signaling Pathway antibodies  IL-6 Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram

Diseases associated with EIF2A elisa kit

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >4 publications with EIF2A and Liver Diseases
 Gastrointestinal Diseases Antibodies  >2 publications with EIF2A and Gastrointestinal Diseases
 Nervous System Diseases Antibodies  >2 publications with EIF2A and Nervous System Diseases
 Atherosclerosis Antibodies  >1 publications with EIF2A and Atherosclerosis
 Cell Transformation, Neoplastic Antibodies  >1 publications with EIF2A and Cell Transformation, Neoplastic
 Fibrosis Antibodies  >1 publications with EIF2A and Fibrosis
 Drug Toxicity Antibodies  >1 publications with EIF2A and Drug Toxicity
 Neoplasms Antibodies  >1 publications with EIF2A and Neoplasms
 Inflammation Antibodies  >1 publications with EIF2A and Inflammation
 Reperfusion Injury Antibodies  >1 publications with EIF2A and Reperfusion Injury

Organs/Tissues associated with EIF2A elisa kit

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with EIF2A and Brain
 Thyroid Antibodies  >2 publications with EIF2A and Thyroid
 Lung Antibodies  >2 publications with EIF2A and Lung
 Liver Antibodies  >2 publications with EIF2A and Liver
 Muscle Antibodies  >2 publications with EIF2A and Muscle
 Blood Antibodies  >1 publications with EIF2A and Blood
 Intestine Antibodies  >1 publications with EIF2A and Intestine
 Pancreas Antibodies  >1 publications with EIF2A and Pancreas
 Kidney Antibodies  >1 publications with EIF2A and Kidney
 Embryonic Tissue Antibodies  >1 publications with EIF2A and Embryonic Tissue
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