Human TBPL1 Recombinant Protein – Cat# MBS143620

TBP-Like 1 (TBPL1) Human Recombinant Protein

Name: TBPL1 Recombinant Protein; TBP-Like 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS143620
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143620

Description: TBPL1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 209 amino acids (1-186 a.a) and having a molecular mass of 23.3kDa.TBPL1 is fused to a 23 amino acid His-tag at N-terminus & purified by… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TBP-Like 1 (TBPL1), Recombinant Protein

Full Product Name

Recombinant Human TBP-Like 1

Product Gene Name

TBPL1 recombinant protein

Product Synonym Names

TBPL1 Human; TBP-Like 1 Human Recombinant; TATA box-binding protein-like protein 1; TBP-like protein 1; 21 kDa TBP-like protein; Second TBP of unique DNA protein; STUD; TATA box-binding protein-related factor 2; TBP-related factor 2; TBP-like factor; TBP-related protein; TBPL1; TLF; TLP; TLP21; TRF2; TRP; MGC:8389; MGC:9620

Sequence

MGSSHHH HHH SSGLVPRGSH MGSMDA DSDV ALDILITNVV CVFRTRCHLN LRKIALEGAN VIYKRDVGKV LMKLRKPRIT ATIWSSGKII CTGATSEEEA KFGARRLARS LQKLGFQVIF TDFKVVNVLA VCNMPFEIRL PEFTKNNRPH ASYEPELHPA VCYRIKSLRA TLQIFSTGSI TVTGPNVKAV ATAVEQIYPF VFESRKEIL.

Host

E Coli

Form/Format

TBPL1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM DTT and 1mM EDTA.
Sterile Filtered colorless solution.

Purity/Purification

Greater than 90.0% as determined by SDS-PAGE.

Preparation and Storage

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Molecular Weight

20,887 Da

OMIM

605521

3D Structure

ModBase 3D Structure for P62380

Product Categories/Family for TBPL1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins

Other Notes

Small volumes of TBPL1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TBPL1 purchase

MBS143620 is a recombinant protein targeting TBPL1. Also known as Recombinant Human TBP-Like 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TBPL1. It may not necessarily be applicable to this product.

NCBI GI #

358439409

NCBI GeneID

9519

NCBI Accession #

NP_001240605.1

UniProt Primary Accession #

P62380

UniProt Secondary Accession #

O95753; Q9BWD5; Q9Z2Z0; A8K8F5

UniProt Related Accession #

P62380

GenBank Nucleotide #

NM_001253676.1

NCBI Official Full Name

TATA box-binding protein-like protein 1

NCBI Official Synonym Full Names

TBP-like 1

NCBI Official Symbol

TBPL1

NCBI Official Synonym Symbols

TLF; TLP; STUD; TRF2; MGC:8389; MGC:9620

UniProt Protein Name

TATA box-binding protein-like protein 1

UniProt Synonym Protein Names

21 kDa TBP-like protein; Second TBP of unique DNA protein; STUD; TATA box-binding protein-related factor 2; TBP-related factor 2; TBP-like factor; TBP-related protein

Protein Family

TATA box-binding protein-like protein

UniProt Gene Name

TBPL1

UniProt Synonym Gene Names

TLF; TLP; TLP21; TRF2; TRP; TBP-like protein 1; STUD; TBP-related factor 2

UniProt Entry Name

TBPL1_HUMAN

NCBI Protein Information

TATA box-binding protein-like protein 1; 21-kDA TBP-like protein; TATA box-binding protein-related factor 2; TBP-related factor 2; TBP-related protein; second TBP of unique DNA protein

NCBI Summary for TBPL1

This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Nov 2011]

UniProt Comments for TBPL1

TBPL1: Does not bind the TATA box. Has DNA-binding ability. Belongs to the TBP family.

Protein type: Cell development/differentiation; DNA-binding; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: cytoplasm; transcription factor TFIIA complex

Molecular Function: DNA binding; transcription coactivator activity

Biological Process: acrosome formation; transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription initiation; spermatid nuclear differentiation; dTTP biosynthetic process

Research Articles on TBPL1

1. results suggest that activation of the p21 upstream promoter is mediated by interaction between specific regions of TLP and p53

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TBPL1 recombinant protein

Reference Product	PubMed Publications
TBP recombinant protein	>14 publications with TBPL1 and TBP
TBPL2 recombinant protein	>2 publications with TBPL1 and TBPL2
FOS recombinant protein	>1 publications with TBPL1 and FOS

Pathways associated with TBPL1 recombinant protein

Products by Pathway	Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Basal Transcription Factors Pathway antibodies	Basal Transcription Factors Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
HTLV-I Infection Pathway antibodies	HTLV-I Infection Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram
Herpes Simplex Infection Pathway antibodies	Herpes Simplex Infection Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram

Diseases associated with TBPL1 recombinant protein

Disease Name	Pubmed Publications
Adenocarcinoma Antibodies	>1 publications with TBPL1 and Adenocarcinoma

Organs/Tissues associated with TBPL1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>4 publications with TBPL1 and Testis
Embryonic Tissue Antibodies	>1 publications with TBPL1 and Embryonic Tissue
Kidney Antibodies	>1 publications with TBPL1 and Kidney