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ARF Gtpase-Activating Protein GIT1 (GIT1) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1436544

MBS1436544 is a recombinant protein targeting Git1. Also known as Recombinant Mouse ARF GTPase-activating protein GIT1 (Git1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1635 / 0.02 mg (E-Coli) +2 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARF GTPase-activating protein GIT1 (Git1), Recombinant Protein
Full Product Name
Recombinant Mouse ARF GTPase-activating protein GIT1 (Git1)
Product Gene Name
Git1 recombinant protein
Product Synonym Gene Name
Git1
Sequence
MSRKGPRAEV CADCSAPDPG WASISRGVLV CDECCSVHRS LGRHISIVKH LRHSAWPPTL LQMVHTLASN GANSIWEHSL LDPAQVQSGR RKANPQDKVH PIKSEFIRAK YQMLAFVHKL PCRDDDGVTA KDLSKQLHSS VRTGNLETCL RLLSLGAQAN FFHPEKGTTP LHVAAKAGQT LQAELLVVYG ADPGSPDVNG RTPIDYARQA GHHELAERLV ECQYELTDRL AFYLCGRKPD HKNGHYIIPQ MADRSRQKCM SQSLDLSELA KAAKKKLQAL SNRLFEELAM DVYDEVDRRE NDAVWLATQN HSTLVTERSA VPFLPVNPEY SATRNQGRQK LARFNAREFA TLIIDILSEA KRRQQGKSLS SPTDNLELSA RSQSELDDQH DYDSVASDED TDQEPLPSAG ATRNNRARSM DSSDLSDGAV TLQEYLELKK ALATSEAKVQ QLMKVNSSLS DELRRLQREI HKLQAENLQL RQPPGPVPPP SLPSERAEHT LMGPGGSTHR RDRQAFSMYE PGSALKPFGG TPGDELATRL QPFHSTELED DAIYSVHVPA GLYRIRKGVS ASSVPFTPSS PLLSCSQEGS RHASKLSRHG SGADSDYENT QSGDPLLGLE GKRFLELSKE DELHPELESL DGDLDPGLPS TEDVILKTEQ VTKNIQELLR AAQEFKHDSF VPCSEKIHLA VTEMASLFPK RPALEPVRSS LRLLNASAYR LQSECRKTVP PEPGAPVDFQ LLTQQVIQCA YDIAKAAKQL VTITTREKKQ
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
85,300 Da
Sequence Positions
1-770aa; Full-Length
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q68FF6
Species
Mouse
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Git1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Git1. It may not necessarily be applicable to this product.

NCBI GI #
51921285
NCBI GeneID
216963
NCBI Accession #
NP_001004144.1
UniProt Primary Accession #
Q68FF6
UniProt Related Accession #
Q68FF6
GenBank Nucleotide #
NM_001004144.1
NCBI Official Full Name
ARF GTPase-activating protein GIT1
NCBI Official Synonym Full Names
G protein-coupled receptor kinase-interactor 1
NCBI Official Symbol
Git1
NCBI Official Synonym Symbols
Cat-1; p95Cat
UniProt Protein Name
ARF GTPase-activating protein GIT1
UniProt Synonym Protein Names
G protein-coupled receptor kinase-interactor 1; GRK-interacting protein 1
Protein Family
Adenylate cyclase activation protein
UniProt Gene Name
Git1
UniProt Synonym Gene Names
ARF GAP GIT1
NCBI Protein Information
ARF GTPase-activating protein GIT1

UniProt Comments for Git1

GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes (). Involved in the regulation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (PubMed:23108400).
Show more

Research Articles on Git1

1. In astrocytes and neural stem cells, we identified G-protein-coupled receptor kinase-interacting protein 1 (GIT1) as a novel mTOR-binding protein, creating a unique mTOR complex lacking Raptor and Rictor

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Git1 recombinant protein

 Products by Pathway  Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram

Diseases associated with Git1 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with Git1 and Neoplasms
 Inflammation Antibodies  >2 publications with Git1 and Inflammation
 Gastrointestinal Diseases Antibodies  >2 publications with Git1 and Gastrointestinal Diseases
 Neurologic Manifestations Antibodies  >2 publications with Git1 and Neurologic Manifestations
 Leukemia Antibodies  >2 publications with Git1 and Leukemia
 Neurodegenerative Diseases Antibodies  >2 publications with Git1 and Neurodegenerative Diseases
 Glioma Antibodies  >2 publications with Git1 and Glioma
 Disease Models, Animal Antibodies  >2 publications with Git1 and Disease Models, Animal
 Neuroblastoma Antibodies  >2 publications with Git1 and Neuroblastoma
 Attention Deficit Disorder with Hyperactivity Antibodies  >2 publications with Git1 and Attention Deficit Disorder with Hyperactivity

Organs/Tissues associated with Git1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >19 publications with Git1 and Brain
 Muscle Antibodies  >14 publications with Git1 and Muscle
 Lung Antibodies  >6 publications with Git1 and Lung
 Kidney Antibodies  >6 publications with Git1 and Kidney
 Embryonic Tissue Antibodies  >6 publications with Git1 and Embryonic Tissue
 Uncharacterized Tissue Antibodies  >2 publications with Git1 and Uncharacterized Tissue
 Eye Antibodies  >2 publications with Git1 and Eye
 Liver Antibodies  >2 publications with Git1 and Liver
 Bone Antibodies  >2 publications with Git1 and Bone
 Bone Marrow Antibodies  >1 publications with Git1 and Bone Marrow
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