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Copper Transport Protein ATOX1 (ATOX1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143661

Description: ATOX1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 88 amino acids (1-68 a.a.) and having a molecular mass of 9.5kDa. ATOX1 is fused to a 20 amino acid His Tag at N-terminus and purified by… More details

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Product Overview

Online Datasheet in PDF
Product Name
Copper Transport Protein ATOX1, Recombinant Protein
Full Product Name
Recombinant Human Copper Transport Protein ATOX1
Product Gene Name
Product Synonym Names
ATOX1 Human; Copper Transport Protein ATOX1 Human Recombinant; Antioxidant protein 1; ATX1; HAH1; Copper transport protein ATOX1; Metal transport protein ATX1; ATOX1; MGC138453; MGC138455
Sequence
MGSSHHH HHH SSGLVPRGSH MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK TVSYLGLE
Host
E Coli
Form/Format
ATOX1 solution containing 20mM Tris pH-8, 1mM DTT and 10% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze thaw cycles.
Molecular Weight
7,402 Da
OMIM
602270
3D Structure
ModBase 3D Structure for O00244

Other Notes

Small volumes of ATOX1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATOX1 purchase

MBS143661 is a recombinant protein targeting ATOX1. Also known as Recombinant Human Copper Transport Protein ATOX1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for ATOX1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
copper transport protein ATOX1
NCBI Official Synonym Full Names
antioxidant 1 copper chaperone
NCBI Official Symbol
ATOX1
NCBI Official Synonym Symbols
ATX1; HAH1
UniProt Protein Name
Copper transport protein ATOX1
UniProt Synonym Protein Names
Metal transport protein ATX1
UniProt Gene Name
ATOX1
UniProt Synonym Gene Names
HAH1
UniProt Entry Name
ATOX1_HUMAN
NCBI Protein Information
copper transport protein ATOX1; ATX1 antioxidant protein 1 homolog; metal transport protein ATX1

NCBI Summary for ATOX1

This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]
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UniProt Comments for ATOX1

ATOX1: Could bind and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense. Belongs to the ATX1 family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: cytosol

Molecular Function: metallochaperone activity; copper ion transmembrane transporter activity; copper ion binding; copper chaperone activity; copper-dependent protein binding

Biological Process: response to reactive oxygen species; cellular copper ion homeostasis; response to oxidative stress; copper ion transport; intracellular copper ion transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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