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L-Amino-Acid Oxidase (IL4I1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1437612

This protein shares the limited similarity with L-amino acid oxidase, and contains the conserved key amino acid residues thought to be involved in catalysis and binding of the flavin adenine dinucleotide cofactor. The expression of this gene can be induced by… More details

$1365 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
L-amino-acid oxidase (IL4I1), Recombinant Protein
Full Product Name
Recombinant Human L-amino-acid oxidase (IL4I1)
Product Gene Name
IL4I1 recombinant protein
Product Synonym Gene Name
IL4I1
Sequence
QDWKAERSQD PFEKCMQDPD YEQLLKVVTW GLNRTLKPQR VIVVGAGVAG LVAAKVLSDA GHKVTILEAD NRIGGRIFTY RDQNTGWIGE LGAMRMPSSH RILHKLCQGL GLNLTKFTQY DKNTWTEVHE VKLRNYVVEK VPEKLGYALR PQEKGHSPED IYQMALNQAL KDLKALGCRK AMKKFERHTL LEYLLGEGNL SRPAVQLLGD VMSEDGFFYL SFAEALRAHS CLSDRLQYSR IVGGWDLLPR ALLSSLSGLV LLNAPVVAMT QGPHDVHVQI ETSPPARNLK VLKADVVLLT ASGPAVKRIT FSPPLPRHMQ EALRRLHYVP ATKVFLSFRR PFWREEHIEG GHSNTDRPSR MIFYPPPREG ALLLASYTWS DAAAAFAGLS REEALRLALD DVAALHGPVV RQLWDGTGVV KRWAEDQHSQ GGFVVQPPAL WQTEKDDWTV PYGRIYFAGE HTAYPHGWVE TAVKSALRAA IKINSRKGPA SDTASPEGHA SDMEGQGHVH GVASSPSHDL AKEEGSHPPV QGQLSLQNTT HTRTSH
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
65,328 Da
Sequence Positions
22-567, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
609742
3D Structure
ModBase 3D Structure for Q96RQ9
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IL4I1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL4I1 purchase

MBS1437612 is a recombinant protein targeting IL4I1. Also known as Recombinant Human L-amino-acid oxidase (IL4I1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for IL4I1. It may not necessarily be applicable to this product.

NCBI GI #
384381475
NCBI GeneID
259307
NCBI Accession #
NP_001244946.1
UniProt Primary Accession #
Q96RQ9
UniProt Secondary Accession #
Q1WMJ3; Q4GZN1; Q4GZN2; Q6P2Q3; Q8TEM5; Q96RQ8
UniProt Related Accession #
Q96RQ9
GenBank Nucleotide #
NM_001258017.1
NCBI Official Full Name
L-amino-acid oxidase isoform 2
NCBI Official Synonym Full Names
interleukin 4 induced 1
NCBI Official Symbol
IL4I1
NCBI Official Synonym Symbols
LAO; FIG1; LAAO
UniProt Protein Name
L-amino-acid oxidase
UniProt Synonym Protein Names
Interleukin-4-induced protein 1; IL4-induced protein 1; Protein Fig-1; hFIG1
UniProt Gene Name
IL4I1
UniProt Synonym Gene Names
FIG1; LAAO; LAO; IL4-induced protein 1; hFIG1
NCBI Protein Information
L-amino-acid oxidase

NCBI Summary for IL4I1

This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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UniProt Comments for IL4I1

Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation ().

Research Articles on IL4I1

1. reviewed SNPs of the IL4I1 isoform 1, which is expressed in lymphoid tissue; the N92D SNP leads to a hyperactive enzyme, while the R102G mutation is hypomorphic; show that IL4I1 activity is not only directed against phenylalanine, as initially described, but also at a lower level against arginine

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IL4I1 recombinant protein

 Products by Pathway  Pathway Diagram
 Abnormal Metabolism In Phenylketonuria Pathway antibodies  Abnormal Metabolism In Phenylketonuria Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Alanine, Aspartate And Glutamate Metabolism Pathway antibodies  Alanine, Aspartate And Glutamate Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Phenylalanine Metabolism Pathway antibodies  Phenylalanine Metabolism Pathway Diagram
 Phenylalanine Metabolism Pathway antibodies  Phenylalanine Metabolism Pathway Diagram
 Phenylalanine, Tyrosine And Tryptophan Biosynthesis Pathway antibodies  Phenylalanine, Tyrosine And Tryptophan Biosynthesis Pathway Diagram
 Phenylalanine, Tyrosine And Tryptophan Biosynthesis Pathway antibodies  Phenylalanine, Tyrosine And Tryptophan Biosynthesis Pathway Diagram

Diseases associated with IL4I1 recombinant protein

 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >5 publications with IL4I1 and Immune System Diseases
 Neoplasms Antibodies  >4 publications with IL4I1 and Neoplasms
 Inflammation Antibodies  >2 publications with IL4I1 and Inflammation
 Disease Models, Animal Antibodies  >1 publications with IL4I1 and Disease Models, Animal

Organs/Tissues associated with IL4I1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >2 publications with IL4I1 and Lymph Node
 Bone Antibodies  >1 publications with IL4I1 and Bone
 Lymph Antibodies  >1 publications with IL4I1 and Lymph
 Spleen Antibodies  >1 publications with IL4I1 and Spleen
 Brain Antibodies  >1 publications with IL4I1 and Brain
 Testis Antibodies  >1 publications with IL4I1 and Testis
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