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Putative Helicase Mov10l1 (MOV10L1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1439520

This gene is similar to a mouse gene that encodes a putative RNA helicase and shows testis-specific expression. Multiple transcript variants encoding different isoforms have been found for this gene. More details

$2590 / 1 mg (E-Coli) +3 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Putative helicase Mov10l1 (MOV10L1), Recombinant Protein
Full Product Name
Recombinant Human Putative helicase Mov10l1 (MOV10L1) , partial
Product Gene Name
MOV10L1 recombinant protein
Product Synonym Gene Name
MOV10L1
Sequence
SNPEQLQAMR HIVTGTTRPA PYIIFGPPGT GKTVTLVEAI KQVVKHLPKA HILACAPSNS GADLLCQRLR VHLPSSIYRL LAPSRDIRMV PEDIKPCCNW DAKKGEYVFP AKKKLQEYRV LITTLITAGR LVSAQFPIDH FTHIFIDEAG HCMEPESLVA IAGLMEVKET GDPGGQLVLA GDPRQLGPVL RSPLTQKHGL GYSLLERLLT YNSLYKKGPD GYDPQFITKL LRNYRSHPTI LDIPNQLYYE GELQACADVV DRERFCRWAG LPRQGFPIIF HGVMGKDERE GNSPSFFNPE EAATVTSYLK LLLAPSSKKG KARLSPRSVG VISPYRKQVE KIRYCITKLD RELRGLDDIK DLKVGSVEEF QGQERSVILI STVRSSQSFV QLDLDFNLGF LKNPKRFNVA VTRAKALLII VGNPLLLGHD PDWKVFLEFC K
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
130,229 Da
Sequence Positions
499-939aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
605794
3D Structure
ModBase 3D Structure for Q9BXT6
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of MOV10L1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MOV10L1 purchase

MBS1439520 is a recombinant protein targeting MOV10L1. Also known as Recombinant Human Putative helicase Mov10l1 (MOV10L1) , partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for MOV10L1. It may not necessarily be applicable to this product.

NCBI GI #
255759906
NCBI GeneID
54456
NCBI Accession #
NP_001157576.1
UniProt Primary Accession #
Q9BXT6
UniProt Secondary Accession #
Q5TGD5; Q8NBD4; Q9NXW3; Q9UFB3; Q9UGX9; A7E211; A8MXC6; B7WPP1; B7Z7R1; F5H403
UniProt Related Accession #
Q9BXT6
GenBank Nucleotide #
NM_001164104.1
NCBI Official Full Name
RNA helicase Mov10l1 isoform 2
NCBI Official Synonym Full Names
Mov10 RISC complex RNA helicase like 1
NCBI Official Symbol
MOV10L1
NCBI Official Synonym Symbols
CHAMP; DJ402G11.8
UniProt Protein Name
RNA helicase Mov10l1
UniProt Synonym Protein Names
Moloney leukemia virus 10-like protein 1
Protein Family
RNA helicase
UniProt Gene Name
MOV10L1
UniProt Synonym Gene Names
MOV10-like protein 1
NCBI Protein Information
RNA helicase Mov10l1

UniProt Comments for MOV10L1

ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5'-3' RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.
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Research Articles on MOV10L1

1. Our results suggest that MOV10L1 gene polymorphisms in the studied infertile males with complete maturation arrest are linked to infertility.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MOV10L1 recombinant protein

 Reference Product  PubMed Publications
 PIWIL2 recombinant protein  >3 publications with MOV10L1 and PIWIL2
 PIWIL1 recombinant protein  >2 publications with MOV10L1 and PIWIL1
 MAEL recombinant protein  >1 publications with MOV10L1 and MAEL
 TDRD9 recombinant protein  >1 publications with MOV10L1 and TDRD9
 PIWIL4 recombinant protein  >1 publications with MOV10L1 and PIWIL4
 HSPA2 recombinant protein  >1 publications with MOV10L1 and HSPA2

Diseases associated with MOV10L1 recombinant protein

 Disease Name  Pubmed Publications
 Gonadal Disorders Antibodies  >2 publications with MOV10L1 and Gonadal Disorders
 Hypertrophy Antibodies  >2 publications with MOV10L1 and Hypertrophy
 Cardiomegaly Antibodies  >1 publications with MOV10L1 and Cardiomegaly
 Heart Diseases Antibodies  >1 publications with MOV10L1 and Heart Diseases
 Infertility, Female Antibodies  >1 publications with MOV10L1 and Infertility, Female

Organs/Tissues associated with MOV10L1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >3 publications with MOV10L1 and Testis
 Ovary Antibodies  >1 publications with MOV10L1 and Ovary
 Brain Antibodies  >1 publications with MOV10L1 and Brain
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