Human GALK1 Recombinant Protein – Cat# MBS143988

Galactokinase 1 (GALK1) Human Recombinant Protein

Name: GALK1 Recombinant Protein; Galactokinase 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS143988
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143988

Description: GALK1 Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 412 amino acids (1-392 a.a.) and having a molecular mass of 44.4 kDa. The GALK1 is fused to 20 amino acid His-Tag at N-terminus and purified by… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Galactokinase 1 (GALK1), Recombinant Protein

Full Product Name

Recombinant Human Galactokinase 1

Product Gene Name

GALK1 recombinant protein

Product Synonym Names

GALK1 Human; Galactokinase 1 Human Recombinant; Galactose kinase; GK1; GALK; EC 2.7.1.6; GALK1

Sequence

MGSSHHH HHH SSGLVPRGSH MAALRQPQVA ELLAEARRAF REEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELM TVLVGSPRKD GLVSLLTTSE GADEPQRLQF PLPTAQRSLE PGTPRWANYV KGVIQYYPAA PLPGFSAVVV SSVPLGGGLS SSASLEVATY TFLQQLCPDS GTIAARAQVC QQAEHSFAGM PCGIMDQFIS LMGQKGHALL IDCRSLETSL VPLSDPKLAV LITNSNVRHS LASSEYPVRR RQCEEVARAL GKESLREVQL EELEAARDLV SKEGFRRARH VVGEIRRTAQ AAAALRRGDY RAFGRLMVES HRSLRDDYEV SCPELDQLVE AALAVPGVYG SRMTGGGFGG CTVTLLEASA APHAMRHIQE HYGGTATFYL SQAADGAKVL CL

Host

E Coli

Form/Format

GALK1 Human solution containing 20mM Tris pH-8, & 10% glycerol.
Sterile filtered colorless solution.

Purity/Purification

Greater than 95.0% as determined by SDS-PAGE.

Preparation and Storage

GALK1 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.

Molecular Weight

45,358 Da

OMIM

230200

3D Structure

ModBase 3D Structure for P51570

Product Categories/Family for GALK1 recombinant protein

Protein Kinases; Enzymes; Protein Kinases

Other Notes

Small volumes of GALK1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GALK1 purchase

MBS143988 is a recombinant protein targeting GALK1. Also known as Recombinant Human Galactokinase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GALK1. It may not necessarily be applicable to this product.

NCBI GI #

4503895

NCBI GeneID

2584

NCBI Accession #

NP_000145.1

UniProt Primary Accession #

P51570

UniProt Secondary Accession #

B2RC07; B4E1G6

UniProt Related Accession #

P51570

GenBank Nucleotide #

NM_000154.1

NCBI Official Full Name

galactokinase

NCBI Official Synonym Full Names

galactokinase 1

NCBI Official Symbol

GALK1

NCBI Official Synonym Symbols

GK1; GALK; HEL-S-19

UniProt Protein Name

Galactokinase

UniProt Synonym Protein Names

Galactose kinase

UniProt Gene Name

GALK1

UniProt Synonym Gene Names

GALK

UniProt Entry Name

GALK1_HUMAN

NCBI Protein Information

galactokinase; epididymis secretory protein Li 19; galactose kinase

NCBI Summary for GALK1

Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population. [provided by RefSeq, Jul 2008]

UniProt Comments for GALK1

GALK1: Major enzyme for galactose metabolism. Defects in GALK1 are the cause of galactosemia II (GALCT2). Galactosemia II is an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses. Belongs to the GHMP kinase family. GalK subfamily.

Protein type: EC 2.7.1.6; Carbohydrate Metabolism - galactose; Kinase, other; Carbohydrate Metabolism - amino sugar and nucleotide sugar

Chromosomal Location of Human Ortholog: 17q24

Cellular Component: membrane; cytoplasm; cytosol

Molecular Function: galactokinase activity; galactose binding; ATP binding

Biological Process: galactose catabolic process; carbohydrate phosphorylation; carbohydrate metabolic process; galactose metabolic process; galactitol metabolic process; pathogenesis

Disease: Galactokinase Deficiency

Research Articles on GALK1

1. The GALK1 gene was included in this interval and direct sequencing.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with GALK1 recombinant protein

Reference Product	PubMed Publications
TK1 recombinant protein	>3 publications with GALK1 and TK1
GALK2 recombinant protein	>2 publications with GALK1 and GALK2
GALE recombinant protein	>1 publications with GALK1 and GALE
GALT recombinant protein	>1 publications with GALK1 and GALT

Pathways associated with GALK1 recombinant protein

Products by Pathway	Pathway Diagram
Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies	Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies	Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
D-galactose Degradation V (Leloir Pathway) antibodies	D-galactose Degradation V (Leloir Pathway) Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Galactose Catabolism Pathway antibodies	Galactose Catabolism Pathway Diagram
Galactose Degradation, Leloir Pathway, Galactose => Alpha-D-glucose-1P antibodies	Galactose Degradation, Leloir Pathway, Galactose => Alpha-D-glucose-1P Diagram
Galactose Degradation, Leloir Pathway, Galactose => Alpha-D-glucose-1P antibodies	Galactose Degradation, Leloir Pathway, Galactose => Alpha-D-glucose-1P Diagram
Galactose Metabolism Pathway antibodies	Galactose Metabolism Pathway Diagram
Galactose Metabolism Pathway antibodies	Galactose Metabolism Pathway Diagram
Glycogen Storage Diseases Pathway antibodies	Glycogen Storage Diseases Pathway Diagram

Diseases associated with GALK1 recombinant protein

Disease Name	Pubmed Publications
Cataract Antibodies	>8 publications with GALK1 and Cataract
Brain Diseases Antibodies	>6 publications with GALK1 and Brain Diseases
Galactosemias Antibodies	>6 publications with GALK1 and Galactosemias
Atrophy Antibodies	>3 publications with GALK1 and Atrophy

Organs/Tissues associated with GALK1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>6 publications with GALK1 and Eye
Blood Antibodies	>4 publications with GALK1 and Blood
Liver Antibodies	>2 publications with GALK1 and Liver
Embryonic Tissue Antibodies	>1 publications with GALK1 and Embryonic Tissue