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Protein Unc-119 Homolog A (UNC119) Bovine Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1439880

This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the… More details

$910 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Protein unc-119 homolog A (UNC119), Recombinant Protein
Full Product Name
Recombinant Bovine Protein unc-119 homolog A (UNC119)
Product Gene Name
UNC119 recombinant protein
Product Synonym Gene Name
UNC119
Sequence
MKVKKGGGGA GTGAEHAPGA SGPNVEPKPE LQAESESGSE SEPEAGPGPR PGPLQRKQPI GPEDVLGLQR ITGDYLCSPE ENIYKIDFVR FKIRDMDSGT VLFEIKKPPA SERLPINPRD LDPNAGRFVR YQFTPAFLRL RQVGATVEFT VGDKPVNNFR MIERHYFRNQ LLKSFDFHFG FCIPSSKNTC EHIYDFPALS EELINEMIRH PYETQSDSFY FVDDRLVMHN KADYSYSGTP
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
26,987 Da
Sequence Positions
1-240, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q3SYR2
Species
Bovine
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of UNC119 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UNC119 purchase

MBS1439880 is a recombinant protein targeting UNC119. Also known as Recombinant Bovine Protein unc-119 homolog A (UNC119). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for UNC119. It may not necessarily be applicable to this product.

NCBI GI #
77736241
NCBI GeneID
538501
NCBI Accession #
NP_001029817.1
UniProt Primary Accession #
Q3SYR2
UniProt Related Accession #
Q3SYR2
GenBank Nucleotide #
NM_001034645.2
NCBI Official Full Name
protein unc-119 homolog A
NCBI Official Synonym Full Names
unc-119 lipid binding chaperone
NCBI Official Symbol
UNC119
UniProt Protein Name
Protein unc-119 homolog A
Protein Family
Protein
UniProt Gene Name
UNC119
NCBI Protein Information
protein unc-119 homolog A

UniProt Comments for UNC119

Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A ().
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Research Articles on UNC119

1. Interaction of transducin with uncoordinated 119 protein (UNC119): implications for the model of transducin trafficking in rod photoreceptors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with UNC119 recombinant protein

 Reference Product  PubMed Publications
 LCK recombinant protein  >7 publications with UNC119 and LCK
 ARL2 recombinant protein  >6 publications with UNC119 and ARL2
 ARL3 recombinant protein  >5 publications with UNC119 and ARL3
 FYN recombinant protein  >4 publications with UNC119 and FYN
 AIPL1 recombinant protein  >1 publications with UNC119 and AIPL1
 GUCA1A recombinant protein  >1 publications with UNC119 and GUCA1A
 LYN recombinant protein  >1 publications with UNC119 and LYN

Pathways associated with UNC119 recombinant protein

 Products by Pathway  Pathway Diagram
 IL-5 Signaling Pathway antibodies  IL-5 Signaling Pathway Diagram
 T Cell Receptor Signaling Pathway antibodies  T Cell Receptor Signaling Pathway Diagram

Diseases associated with UNC119 recombinant protein

 Disease Name  Pubmed Publications
 Retinitis Pigmentosa Antibodies  >5 publications with UNC119 and Retinitis Pigmentosa
 Disease Models, Animal Antibodies  >3 publications with UNC119 and Disease Models, Animal
 Nervous System Diseases Antibodies  >2 publications with UNC119 and Nervous System Diseases
 Neural Tube Defects Antibodies  >2 publications with UNC119 and Neural Tube Defects
 Dermatitis Antibodies  >1 publications with UNC119 and Dermatitis
 Fibrosis Antibodies  >1 publications with UNC119 and Fibrosis
 Nerve Degeneration Antibodies  >1 publications with UNC119 and Nerve Degeneration
 Abnormalities, Multiple Antibodies  >1 publications with UNC119 and Abnormalities, Multiple
 Inflammation Antibodies  >1 publications with UNC119 and Inflammation

Organs/Tissues associated with UNC119 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with UNC119 and Brain
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