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Granulysin (GNLY) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS143996

Description: GNLY Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 159 amino acids and fused to a double His Tag (N+C terminus) and having a total molecular mass of 18.1 kDa.The GNLY is purified by proprietary… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Granulysin (GNLY), Recombinant Protein
Full Product Name
Recombinant Human Granulysin
Product Gene Name
Product Synonym Names
GNLY Human; Granulysin Human Recombinant; LAG2; Lymphokine LAG-2; TLA519; NKG5; LAG2; D2S69E; Granulysin; T-cell activation protein 519; GNLY; D2S69E
Sequence
MGSSHHHHHH SSGLVP RGSHMMEGLV FSRLSPEYYD LARAHLRDEE KSCPCLAQEG PQGDLLTKTQ ELGRDYRTCL TIVQKLKKMV DKPTQRSVSN AATRVCRTGR SRWRDVCRNF MRRYQSRVTQ GLVAGETAQQ ICEDLRLCIP STGPLGSHHH HHH
Host
E Coli
Form/Format
The Granulysin protein was lyophilized from a concentrated (1mg/ml) solution containing no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
Lyophilized Granulysin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Granulysin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
OMIM
188855
3D Structure
ModBase 3D Structure for P22749
Solubility
It is recommended to reconstitute the lyophilized Granulysin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Other Notes

Small volumes of GNLY recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNLY purchase

MBS143996 is a recombinant protein targeting GNLY. Also known as Recombinant Human Granulysin. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GNLY. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
granulysin isoform 2
NCBI Official Synonym Full Names
granulysin
NCBI Official Symbol
GNLY
NCBI Official Synonym Symbols
519; LAG2; NKG5; LAG-2; D2S69E; TLA519
UniProt Protein Name
Granulysin
UniProt Synonym Protein Names
Lymphokine LAG-2; Protein NKG5; T-cell activation protein 519
Protein Family
UniProt Gene Name
GNLY
UniProt Synonym Gene Names
LAG2; NKG5; TLA519
UniProt Entry Name
GNLY_HUMAN
NCBI Protein Information
granulysin; T-cell activation protein 519; T-lymphocyte activation gene 519; lymphocyte-activation gene 2; lymphokine LAG-2

NCBI Summary for GNLY

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for GNLY

GNLY: Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: extracellular space

Biological Process: killing of cells of another organism; defense response to bacterium; cellular defense response; defense response to fungus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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