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Mitochondrial Trans-2-Enoyl-Coa Reductase (MECR) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144016

Description: MECR Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 341 amino acids (54-373 a.a.) and having a molecular mass of 49.8 kDa. The MECR is fused to 21 amino acid His-Tag at N-terminus and purified by… More details

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Product Documentation
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR), Recombinant Protein
Full Product Name
Recombinant Human Mitochondrial Trans-2-Enoyl-CoA Reductase
Product Gene Name
Product Synonym Names
MECR Human; Mitochondrial Trans-2-Enoyl-CoA Reductase Human Recombinant; NRBF1; CGI-63; FASN2B; EC 1.3.1.38; MECR; Mitochondrial Trans-2-Enoyl-CoA Reductase
Sequence
MGSSHHH HHH SSGLVPRGSH MPAKVV ELKN LELAAVRGSD VRVKMLAAPI NPSDINMIQG NYGLLPELPA VGGNEGVAQV VAVGSNVTGL KPGDWVIPAN AGLGTWRTEA VFSEEALIQV PSDIPLQSAA TLGVNPCTAY RMLMDFEQLQ PGDSVIQNAS NSGVGQAVIQ IAAALGLRTI NVVRDRPDIQ KLSDRLKSLG AEHVITEEEL RRPEMKNFFK DMPQPRLALN CVGGKSSTEL LRQLARGGTM VTYGGMAKQP VVASVSLLIF KDLKLRGFWL SQWKKDHSPD QFKELILTLC DLIRRGQLTA PACSQVPLQD YQSALEASMK PFISSKQILT M
Host
E Coli
Form/Format
MECR Human solution containing 20mM Trsi pH-8, 0.2M NaCl, 5mM DTT & 20% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
MECR Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
Molecular Weight
32,228 Da
OMIM
608205
3D Structure
ModBase 3D Structure for Q9BV79

Product Categories/Family for MECR recombinant protein

Other Notes

Small volumes of MECR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MECR purchase

MBS144016 is a recombinant protein targeting MECR. Also known as Recombinant Human Mitochondrial Trans-2-Enoyl-CoA Reductase. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MECR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
trans-2-enoyl-CoA reductase, mitochondrial isoform b
NCBI Official Synonym Full Names
mitochondrial trans-2-enoyl-CoA reductase
NCBI Official Symbol
MECR
NCBI Official Synonym Symbols
NRBF1; CGI-63; FASN2B
UniProt Protein Name
Trans-2-enoyl-CoA reductase, mitochondrial
UniProt Synonym Protein Names
Nuclear receptor-binding factor 1; HsNrbf-1; NRBF-1
UniProt Gene Name
MECR
UniProt Synonym Gene Names
NBRF1; HsNrbf-1; NRBF-1
UniProt Entry Name
MECR_HUMAN
NCBI Protein Information
trans-2-enoyl-CoA reductase, mitochondrial; homolog of yeast 2-enoyl thioester reductase; mitochondrial 2-enoyl thioester reductase; nuclear receptor binding factor 1

UniProt Comments for MECR

MECR: Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid Metabolism - fatty acid elongation in mitochondria; Oxidoreductase; EC 1.3.1.38

Chromosomal Location of Human Ortholog: 1p35.3

Cellular Component: mitochondrion; nucleus

Molecular Function: zinc ion binding; trans-2-enoyl-CoA reductase (NADPH) activity

Biological Process: fatty acid metabolic process; fatty acid biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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