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Nad(p)h Dehydrogenase Quinone 2 (NQO2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144019

Description: NQO2 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 251amino acids (1-231 a.a.) and having a molecular mass of 28.1 kDa. NQO2 protein is fused to a 20 amino acid His-Tag at N-terminus and purified… More details

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Product Overview

Online Datasheet in PDF
Product Name
NAD(P)H Dehydrogenase Quinone 2 (NQO2), Recombinant Protein
Full Product Name
Recombinant Human NAD(P)H Dehydrogenase Quinone 2
Product Gene Name
Product Synonym Names
NQO2 Human; NAD(P)H Dehydrogenase Quinone 2 Human Recombinant; DHQV; DIA6; QR2; EC 1.10.99.2; NMOR2; NQO2; NRH:quinone oxidoreductase 2; NRH dehydrogenase [quinone] 2; Ribosyldihydronicotinamide dehydrogenase [quinone]
Sequence
MGSSHHH HHH SSGLVPRGSH MAGKKVLIVY AHQEPKSFNG SLKNVAVDEL SRQGCTVTVS DLYAMNFEPR ATDKDITGTL SNPEVFNYGV ETHEAYKQRS LASDITDEQK KVREADLVIF QFPLYWFSVP AILKGWMDRV LCQGFAFDIP GFYDSGLLQG KLALLSVTTG GTAEMYTKTG VNGDSRYFLW PLQHGTLHFC GFKVLAPQIS FAPEIASEEE RKGMVAAWSQ RLQTIWKEEP IPCTAHWHFG Q
Host
E Coli
Form/Format
NQO2 Human solution (1mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT & 10% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Preparation and Storage
NQO2 Human although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
Molecular Weight
25,919 Da
OMIM
160998
3D Structure
ModBase 3D Structure for P16083

Product Categories/Family for NQO2 recombinant protein

Other Notes

Small volumes of NQO2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NQO2 purchase

MBS144019 is a recombinant protein targeting NQO2. Also known as Recombinant Human NAD(P)H Dehydrogenase Quinone 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NQO2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ribosyldihydronicotinamide dehydrogenase
NCBI Official Synonym Full Names
NAD(P)H dehydrogenase, quinone 2
NCBI Official Symbol
NQO2
NCBI Official Synonym Symbols
QR2; DHQV; DIA6; NMOR2
UniProt Protein Name
Ribosyldihydronicotinamide dehydrogenase [quinone]
UniProt Synonym Protein Names
NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2
UniProt Gene Name
NQO2
UniProt Synonym Gene Names
NMOR2; QR2
UniProt Entry Name
NQO2_HUMAN
NCBI Protein Information
ribosyldihydronicotinamide dehydrogenase [quinone]; ribosyldihydronicotinamide dehydrogenase [quinone]; NAD(P)H menadione oxidoreductase-1, dioxin-inducible-2; NRH:quinone oxidoreductase 2; quinone reductase 2

NCBI Summary for NQO2

This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
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UniProt Comments for NQO2

NQO2: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. Belongs to the NAD(P)H dehydrogenase (quinone) family.

Protein type: Oxidoreductase; EC 1.10.99.2

Chromosomal Location of Human Ortholog: 6p25.2

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: electron carrier activity; dihydronicotinamide riboside quinone reductase activity; NADPH dehydrogenase (quinone) activity; metal ion binding

Biological Process: memory

Disease: Breast Cancer
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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