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Related RAS Viral (RRAS) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144043

Description: RRAS Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 235 amino acids (1-215 a.a.) and having a molecular mass of 25.3 kDa. RRAS protein is fused to a 20 amino acid His-Tag at N-terminus and… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Related RAS Viral (RRAS), Recombinant Protein
Full Product Name
Recombinant Human Related RAS Viral (r-ras) Oncogene Homolog
Product Gene Name
RRAS recombinant protein
Product Synonym Names
RRAS Human; Related RAS Viral (r-ras) Oncogene Homolog Human Recombinant; Ras-Related Protein R-Ras; p23; RRAS
Sequence
MGSSHHH HHH SSGLVPRGSH MSSGAASGTG RGRPRGGGPG PGDPPPSETH KLVVVGGGGV GKSALTIQFI QSYFVSDYDP TIEDSYTKIC SVDGIPARLD ILDTAGQEEF GAMREQYMRA GHGFLLVFAI NDRQSFNEVG KLFTQILRVK DRDDFPVVLV GNKADLESQR QVPRSEASAF GASHHVAYFE ASAKLRLNVD EAFEQLVRAV RKYQEQELPP SPPSAPRKKG GGCPC
Host
E Coli
Form/Format
RRAS Human solution containing 20mM Trsi HCL pH-8, 0.1M NaCl and 10% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Preparation and Storage
RRAS human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
Molecular Weight
23,480 Da
OMIM
165090
3D Structure
ModBase 3D Structure for P10301

Product Categories/Family for RRAS recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Related RAS Viral (r-ras) Oncogene

Other Notes

Small volumes of RRAS recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RRAS purchase

MBS144043 is a recombinant protein targeting RRAS. Also known as Recombinant Human Related RAS Viral (r-ras) Oncogene Homolog. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RRAS. It may not necessarily be applicable to this product.

NCBI GI #
5454028
NCBI GeneID
6237
NCBI Accession #
NP_006261.1
UniProt Primary Accession #
P10301
UniProt Secondary Accession #
Q6FH12
UniProt Related Accession #
P10301
GenBank Nucleotide #
NM_006270.3
NCBI Official Full Name
ras-related protein R-Ras
NCBI Official Synonym Full Names
related RAS viral (r-ras) oncogene homolog
NCBI Official Symbol
RRAS
UniProt Protein Name
Ras-related protein R-Ras
UniProt Synonym Protein Names
p23
Protein Family
Ras-related protein
UniProt Gene Name
RRAS
UniProt Entry Name
RRAS_HUMAN
NCBI Protein Information
ras-related protein R-Ras; Oncogene RRAS; p23

NCBI Summary for RRAS

The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015]

UniProt Comments for RRAS

RRas: a small G protein of the Ras family. Promotes focal adhesion formation by signaling to FAK and p130(Cas). Promotes tumor growth of cervical epithelial cells and increases their migration potential over collagen through a pathway that involves PI 3-K.

Protein type: G protein, monomeric, Ras; G protein; Motility/polarity/chemotaxis; G protein, monomeric

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: focal adhesion; plasma membrane

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; protein complex binding

Biological Process: axon guidance; synaptic transmission; positive regulation of angiogenesis; metabolic process; Ras protein signal transduction; leukocyte differentiation; regulation of protein kinase B signaling cascade; negative regulation of cell migration
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Research Articles on RRAS

1. Contradicting the positive association reported in previous studies, our results indicate that R-Ras activation may negatively regulate the transformation of breast epithelial cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RRAS recombinant protein

 Reference Product  PubMed Publications
 SRC recombinant protein  >5 publications with RRAS and SRC
 SEMA4D recombinant protein  >3 publications with RRAS and SEMA4D
 RAF1 recombinant protein  >3 publications with RRAS and RAF1
 EPHB2 recombinant protein  >1 publications with RRAS and EPHB2

Pathways associated with RRAS recombinant protein

 Products by Pathway  Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 CREB Phosphorylation Through The Activation Of Ras Pathway antibodies  CREB Phosphorylation Through The Activation Of Ras Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EPHB Forward Signaling Pathway antibodies  EPHB Forward Signaling Pathway Diagram
 G Protein Signaling Pathways antibodies  G Protein Signaling Pathways Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
 MAPK Cascade Pathway antibodies  MAPK Cascade Pathway Diagram

Diseases associated with RRAS recombinant protein

 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >11 publications with RRAS and Cell Transformation, Neoplastic
 Nervous System Diseases Antibodies  >7 publications with RRAS and Nervous System Diseases
 Breast Neoplasms Antibodies  >6 publications with RRAS and Breast Neoplasms
 Brain Diseases Antibodies  >6 publications with RRAS and Brain Diseases
 Inflammation Antibodies  >5 publications with RRAS and Inflammation
 Neoplasm Metastasis Antibodies  >4 publications with RRAS and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >3 publications with RRAS and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >2 publications with RRAS and Liver Neoplasms
 Uterine Cervical Neoplasms Antibodies  >2 publications with RRAS and Uterine Cervical Neoplasms
 Fibrosis Antibodies  >2 publications with RRAS and Fibrosis

Organs/Tissues associated with RRAS recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >15 publications with RRAS and Brain
 Muscle Antibodies  >9 publications with RRAS and Muscle
 Testis Antibodies  >7 publications with RRAS and Testis
 Bone Antibodies  >7 publications with RRAS and Bone
 Heart Antibodies  >6 publications with RRAS and Heart
 Connective Tissue Antibodies  >4 publications with RRAS and Connective Tissue
 Embryonic Tissue Antibodies  >4 publications with RRAS and Embryonic Tissue
 Prostate Antibodies  >4 publications with RRAS and Prostate
 Lymph Antibodies  >3 publications with RRAS and Lymph
 Kidney Antibodies  >3 publications with RRAS and Kidney
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