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Rho Family Gtpase 3 (RND3) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144044

Description: RND3 Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 261 amino acids (1-241 a.a.) and having a molecular mass of 29.2 kDa. The RND3 is fused to a 20 amino acid His-Tag at N-terminus and purified by… More details

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Product Overview

Online Datasheet in PDF
Product Name
Rho Family GTPase 3 (RND3), Recombinant Protein
Full Product Name
Recombinant Human Rho Family GTPase 3
Product Gene Name
Product Synonym Names
RND3 Human; Rho Family GTPase 3 Human Recombinant; ARHE; memB; Rho8; RhoE; Rho-related GTP-binding protein RhoE; Protein MemB; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rnd3
Sequence
MGSSHHH HHH SSGLVPRGSH MKERRASQKL SSKSIMDPNQ NVKCKIVVVG DSQCGKTALL HVFAKDCFPE NYVPTVFENY TASFEIDTQR IELSLWDTSG SPYYDNVRPL SYPDSDAVLI CFDISRPETL DSVLKKWKGE IQEFCPNTKM LLVGCKSDLR TDVSTLVELS NHRQTPVSYD QGANMAKQIG AATYIECSAL QSENSVRDIF HVATLACVNK TNKNVKRNKS QRATKRISHM PSRPELSAVA TDLRKDKAKS C
Host
E Coli
Form/Format
RND3 Human solution containing 20mM Tris-HCl pH-8, 1mM DTT, 1mM EDTA, 0.1M NaCl & 40% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Molecular Weight
27,368 Da
OMIM
602924
3D Structure
ModBase 3D Structure for P61587

Other Notes

Small volumes of RND3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RND3 purchase

MBS144044 is a recombinant protein targeting RND3. Also known as Recombinant Human Rho Family GTPase 3. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RND3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rho-related GTP-binding protein RhoE
NCBI Official Synonym Full Names
Rho family GTPase 3
NCBI Official Symbol
RND3
NCBI Official Synonym Symbols
ARHE; Rho8; RhoE; memB
UniProt Protein Name
Rho-related GTP-binding protein RhoE
UniProt Synonym Protein Names
Protein MemB; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rnd3
UniProt Gene Name
RND3
UniProt Synonym Gene Names
ARHE; RHO8; RHOE
UniProt Entry Name
RND3_HUMAN
NCBI Protein Information
rho-related GTP-binding protein RhoE; protein MemB; ras homolog gene family, member E; rho-related GTP-binding protein Rho8; small GTP binding protein Rho8

NCBI Summary for RND3

This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
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UniProt Comments for RND3

RhoE: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Binds ROCK1. Interacts with UBXD5. Ubiquitous. Belongs to the small GTPase superfamily. Rho family.

Protein type: G protein, monomeric; G protein, monomeric, Rho; Motility/polarity/chemotaxis; G protein

Chromosomal Location of Human Ortholog: 2q23.3

Cellular Component: Golgi membrane; focal adhesion

Molecular Function: GTPase activity; protein binding; GTP binding

Biological Process: metabolic process; small GTPase mediated signal transduction; cell adhesion; actin cytoskeleton organization and biogenesis
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Research Articles on RND3

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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