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Secretory Leukocyte Peptidase Inhibitor (SLPI) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144051

SLPI Recombinant E.coli produced in E.Coli is a single, non-glycosylated polypeptide chain containing 128 amino acids (26-132 a.a.) and having a molecular mass of 14 kDa. The SLPI is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Secretory Leukocyte Peptidase Inhibitor (SLPI), Recombinant Protein
Full Product Name
Recombinant Human Secretory Leukocyte Peptidase Inhibitor
Product Gene Name
Product Synonym Names
SLPI Human; Secretory Leukocyte Peptidase Inhibitor Human Recombinant; Antileukoproteinase; ALK1; ALP; BLPI; HUSI; HUSI-I; MPI; WAP4; WFDC4; WAP four-disulfide core domain protein 4; Protease inhibitor WAP4; Seminal proteinase inhibitor; Mucus proteinase inhibitor
Sequence
MGSSHHH HHH SSGLVPRGSH MSGKSF KAGV CPPKKSAQCL RYKKPECQSD WQCPGKKRCC PDTCGIKCLD PVDTPNPTRR KPGKCPVTYG QCLMLNPPNF CEMDGQCKRD LKCCMGMCGK SCVSPVKA
Form/Format
0.25 mg/mL solution containing 20mM Tris-HCl pH-8.0, 2mM DTT, 0.1M NaCl & 20% glycerol.
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degrees if entire vial will be used within 2-4 weeks.
Store, frozen at -20 degrees for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Sequence Positions
26-132
OMIM
107285
3D Structure
ModBase 3D Structure for P03973
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.

Other Notes

Small volumes of SLPI recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLPI purchase

MBS144051 is a recombinant protein targeting SLPI. Also known as Recombinant Human Secretory Leukocyte Peptidase Inhibitor.

Additional Details

NCBI/Uniprot data below describe general gene information for SLPI. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
antileukoproteinase
NCBI Official Synonym Full Names
secretory leukocyte peptidase inhibitor
NCBI Official Symbol
SLPI
NCBI Official Synonym Symbols
ALP; MPI; ALK1; BLPI; HUSI; WAP4; WFDC4; HUSI-I
UniProt Protein Name
Antileukoproteinase
UniProt Synonym Protein Names
BLPI; HUSI-1; Mucus proteinase inhibitor; MPI; Protease inhibitor WAP4; Secretory leukocyte protease inhibitor; Seminal proteinase inhibitor; WAP four-disulfide core domain protein 4
Protein Family
UniProt Gene Name
SLPI
UniProt Synonym Gene Names
WAP4; WFDC4; ALP; MPI
UniProt Entry Name
SLPI_HUMAN
NCBI Protein Information
antileukoproteinase; HUSI-1; WAP four-disulfide core domain protein 4; mucus proteinase inhibitor; protease inhibitor WAP4; secretory leukocyte protease inhibitor (antileukoproteinase); seminal proteinase inhibitor

NCBI Summary for SLPI

This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity. [provided by RefSeq, Nov 2014]
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UniProt Comments for SLPI

SLPI: Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. May prevent elastase-mediated damage to oral and possibly other mucosal tissues.

Protein type: Secreted, signal peptide; Secreted; Inhibitor

Chromosomal Location of Human Ortholog: 20q12

Cellular Component: extracellular matrix

Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; enzyme binding; endopeptidase inhibitor activity

Biological Process: negative regulation of viral genome replication; negative regulation of protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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