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Snurportin 1 (SNUPN) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144054

Description: SNUPN Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 380 amino acids (1-360 a.a.) and having a molecular mass of 43.3 kDa. The SNUPN is fused to 20 amino acid His-Tag at N-terminus and purified by… More details

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Product Overview

Online Datasheet in PDF
Product Name
Snurportin 1 (SNUPN), Recombinant Protein
Full Product Name
Recombinant Human Snurportin 1
Product Gene Name
Product Synonym Names
SNUPN Human; Snurportin 1 Human Recombinant; KPNBL; RNUT1; Snurportin1; SPN1; RNA U transporter 1
Sequence
MGSSHHH HHH SSGLVPRGSH MEELSQALAS SFSVSQDLNS TAAPHPRLSQ YKSKYSSLEQ SERRRRLLEL QKSKRLDYVN HARRLAEDDW TGMESEEENK KDDEEMDIDT VKKLPKHYAN QLMLSEWLID VPSDLGQEWI VVVCPVGKRA LIVASRGSTS AYTKSGYCVN RFSSLLPGGN RRNSTAKDYT ILDCIYNEVN QTYYVLDVMC WRGHPFYDCQ TDFRFYWMHS KLPEEEGLGE KTKLNPFKFV GLKNFPCTPE SLCDVLSMDF PFEVDGLLFY HKQTHYSPGS TPLVGWLRPY MVSDVLGVAV PAGPLTTKPD YAGHQLQQIM EHKKSQKEGM KEKLTHKASE NGHYELEHLS TPKLKGSSHS PDHPGCLMEN
Host
E Coli
Form/Format
SNUPN Human solution containing 20mM Tris pH-8, 2mM DTT, 0.1M NaCl, & 10% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
SNUPN Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
Molecular Weight
41,143 Da
OMIM
607902
3D Structure
ModBase 3D Structure for O95149

Other Notes

Small volumes of SNUPN recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNUPN purchase

MBS144054 is a recombinant protein targeting SNUPN. Also known as Recombinant Human Snurportin 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for SNUPN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
snurportin-1
NCBI Official Synonym Full Names
snurportin 1
NCBI Official Symbol
SNUPN
NCBI Official Synonym Symbols
KPNBL; RNUT1; Snurportin1
UniProt Protein Name
Snurportin-1
UniProt Synonym Protein Names
RNA U transporter 1
Protein Family
UniProt Gene Name
SNUPN
UniProt Synonym Gene Names
RNUT1; SPN1
UniProt Entry Name
SPN1_HUMAN
NCBI Protein Information
snurportin-1; RNA U transporter 1; RNA, U transporter 1

NCBI Summary for SNUPN

The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for SNUPN

RNUT1: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family.

Protein type: Nuclear import; RNA-binding

Chromosomal Location of Human Ortholog: 15q24.2

Cellular Component: nuclear pore; cytosol

Molecular Function: protein transporter activity; RNA cap binding

Biological Process: spliceosomal snRNP biogenesis; protein import into nucleus; gene expression
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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