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Glucosamine-6-Phosphate Deaminase 1 (GNPDA1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144097

Description: GNPDA1 Recombinant Human produced in E Coli is a single, non-glycosylated, polypeptide chain containing 309 amino acids (1-289) and having a molecular mass of 34.8 kDa.GNPDA1 is fused to a 20 amino macid His-Tag at N-terminus and purified by… More details

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Product Overview

Online Datasheet in PDF
Product Name
Glucosamine-6-Phosphate Deaminase 1 (GNPDA1), Recombinant Protein
Full Product Name
Recombinant Human Glucosamine-6-Phosphate Deaminase 1
Product Synonym Names
GNPDA1 Human; Glucosamine-6-Phosphate Deaminase 1 Human Recombinant; GNP1; GNPDA; GNPI; GPI; HLN; Oscillin
Sequence
MGSSHHHHHH SSGLVPRGSH MKLIILEHYS QASEWAAKYI RNRIIQFNPG PEKYFTLGLP TGSTPLGCYK KLIEYYKNGD LSFKYVKTFN MDEYVGLPRD HPESYHSFMW NNFFKHIDIH PENTHILDGN AVDLQAECDA FEEKIKAAGG IELFVGGIGP DGHIAFNEPG SSLVSRTRVK TLAMDTILAN ARFFDGELTK VPTMALTVGV GTVMDAREVM ILITGAHKAF ALYKAIEEGV NHMWTVSAFQ QHPRTVFVCD EDATLELKVK TVKYFKGLML VHNKLVDPLY SIKEKETEKS QSSKKPYSD
Host
E Coli
Form/Format
1 mg/ml solution containing 20mM Tris Hcl buffer pH-8, 1mM DTT, 50mM NaCl and 20% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
GNPDA1 Human Recombinant although stable at 4 degree C for 1 week, should be stored below -18 degree C.Please prevent freeze-thaw cycles.
Molecular Weight
24,047 Da
OMIM
601798
3D Structure
ModBase 3D Structure for P46926

Product Categories/Family for GNPDA1 recombinant protein

Other Notes

Small volumes of GNPDA1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNPDA1 purchase

MBS144097 is a recombinant protein targeting GNPDA1. Also known as Recombinant Human Glucosamine-6-Phosphate Deaminase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GNPDA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
glucosamine-6-phosphate isomerase 1
NCBI Official Synonym Full Names
glucosamine-6-phosphate deaminase 1
NCBI Official Symbol
GNPDA1
NCBI Official Synonym Symbols
GPI; HLN; GNP1; GNPI; GNPDA
UniProt Protein Name
Glucosamine-6-phosphate isomerase 1
UniProt Synonym Protein Names
Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin
UniProt Gene Name
GNPDA1
UniProt Synonym Gene Names
GNPI; HLN; KIAA0060; GNPDA 1; GlcN6P deaminase 1
UniProt Entry Name
GNPI1_HUMAN
NCBI Protein Information
glucosamine-6-phosphate isomerase 1; GNPDA 1; glcN6P deaminase 1; oscillin

NCBI Summary for GNPDA1

Glucosamine-6-phosphate deaminase (EC 3.5.99.6) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium (Arreola et al., 2003 [PubMed 12965206]).[supplied by OMIM, Jan 2010]

UniProt Comments for GNPDA1

GNPDA1: Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.

Protein type: Isomerase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Hydrolase; EC 3.5.99.6

Chromosomal Location of Human Ortholog: 5q21

Cellular Component: cytoplasm

Molecular Function: glucosamine-6-phosphate deaminase activity; hydrolase activity

Biological Process: generation of precursor metabolites and energy; single fertilization; glucosamine catabolic process; N-acetylglucosamine metabolic process; carbohydrate metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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