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Guanosine Monophosphate Reductase 2 (GMPR2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144130

Description: GMPR2 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 368 amino acids (1-348 a.a.) and having a molecular mass of 40 kDa. GMPR2 is fused to a 20 amino acid His-tag at N-terminus and purified by… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Guanosine Monophosphate Reductase 2 (GMPR2), Recombinant Protein
Full Product Name
Recombinant Human Guanosine Monophosphate Reductase 2
Product Gene Name
Product Synonym Names
GMPR2 Human; Guanosine Monophosphate Reductase 2 Human Recombinant; GMP reductase 2; Guanosine 5''-monophosphate oxidoreductase 2
Sequence
MGSSHHHHHH SSGLVPRGSH MPHIDNDVKL DFKDVLLRPK RSTLKSRSEV DLTRSFSFRN SKQTYSGVPI IAANMDTVGT FEMAKVLCKF SLFTAVHKHY SLVQWQEFAG QNPDCLEHLA ASSGTGSSDF EQLEQILEAI PQVKYICLDV ANGYSEHFVE FVKDVRKRFP QHTIMAGNVV TGEMVEELIL SGADIIKVGI GPGSVCTTRK KTGVGYPQLS AVMECADAAH GLKGHIISDG GCSCPGDVAK AFGAGADFVM LGGMLAGHSE SGGELIERDG KKYKLFYGMS SEMAMKKYAG GVAEYRASEG KTVEVPFKGD VEHTIRDILG GIRSTCTYVG AAKLKELSRR TTFIRVTQQV NPIFSEAC
Host
E Coli
Form/Format
GMPR2 1mg/ml solution contains 20mM Tris pH-8, 1mM DTT and 10% glycerol.
Sterile filtered colorless solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Preparation and Storage
GMPR2 Human Recombinant although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
Molecular Weight
34,597 Da
OMIM
610781
3D Structure
ModBase 3D Structure for Q9P2T1

Product Categories/Family for GMPR2 recombinant protein

Other Notes

Small volumes of GMPR2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GMPR2 purchase

MBS144130 is a recombinant protein targeting GMPR2. Also known as Recombinant Human Guanosine Monophosphate Reductase 2. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GMPR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GMP reductase 2 isoform 2
NCBI Official Synonym Full Names
guanosine monophosphate reductase 2
NCBI Official Symbol
GMPR2
UniProt Protein Name
GMP reductase 2
UniProt Synonym Protein Names
Guanosine 5'-monophosphate oxidoreductase 2; Guanosine monophosphate reductase 2
Protein Family
UniProt Gene Name
GMPR2
UniProt Synonym Gene Names
Guanosine monophosphate reductase 2
UniProt Entry Name
GMPR2_HUMAN
NCBI Protein Information
GMP reductase 2; guanosine 5'-monophosphate oxidoreductase 2; guanosine monophosphate reductase isolog

UniProt Comments for GMPR2

GMPR2: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation. Belongs to the IMPDH/GMPR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.7.1.7; Nucleotide Metabolism - purine; Oxidoreductase

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: cytosol

Molecular Function: GMP reductase activity; metal ion binding

Biological Process: nucleobase, nucleoside and nucleotide metabolic process; purine salvage; GMP metabolic process; purine base metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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