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Phosphatidylinositol Transfer Protein, Beta (PITPNB) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144178

Description: PITPNB Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 291 amino acids (1-271 a.a.) and having a molecular mass of 33.7kDa. The PITPNB is purified… More details

$250 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Phosphatidylinositol Transfer Protein, Beta (PITPNB), Recombinant Protein
Full Product Name
Recombinant Human Phosphatidylinositol Transfer Protein, Beta
Product Synonym Names
PITPNB Human; Phosphatidylinositol Transfer Protein Beta Human Recombinant; Phosphatidylinositol transfer protein beta isoform; PI-TP-beta; PtdIns transfer protein beta; PtdInsTP beta; PITPNB; VIB1B; PtdInsTP
Sequence
MGSSHHH HHH SSGLVPRGSH MVLIKEFRVV LPCSVQEYQV GQLYSVAEAS KNETGGGEGI EVLKNEPYEK DGEKGQYTHK IYHLKSKVPA FVRMIAPEGS LVFHEKAWNA YPYCRTIVTN EYMKDDFFIK IETWHKPDLG TLENVHGLDP NTWKTVEIVH IDIADRSQVE PADYKADEDP ALFQSVKTKR GPLGPNWKKE LANSPDCPQM CAYKLVTIKF KWWGLQSKVE NFIQKQEKRI FTNFHRQLFC WIDKWIDLTM EDIRRMEDET QKELETMRKR GSVRGTSAAD V
Host
E Coli
Form/Format
The PITPNB solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Preparation and Storage
PITPNB should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Molecular Weight
31,700 Da
OMIM
606876
3D Structure
ModBase 3D Structure for P48739

Other Notes

Small volumes of PITPNB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PITPNB purchase

MBS144178 is a recombinant protein targeting PITPNB. Also known as Recombinant Human Phosphatidylinositol Transfer Protein, Beta. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PITPNB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phosphatidylinositol transfer protein beta isoform isoform 2
NCBI Official Synonym Full Names
phosphatidylinositol transfer protein, beta
NCBI Official Symbol
PITPNB
NCBI Official Synonym Symbols
VIB1B; PtdInsTP; PI-TP-beta
UniProt Protein Name
Phosphatidylinositol transfer protein beta isoform
UniProt Gene Name
PITPNB
UniProt Synonym Gene Names
PI-TP-beta; PtdIns transfer protein beta; PtdInsTP beta
UniProt Entry Name
PIPNB_HUMAN
NCBI Protein Information
phosphatidylinositol transfer protein beta isoform; PtdIns transfer protein beta; phosphotidylinositol transfer protein, beta

NCBI Summary for PITPNB

This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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UniProt Comments for PITPNB

PITPNB: transfers phosphatidylinositol, phosphatidylcholine and sphingomyelin between membrane bilayers. Associates mainly with the trans-Golgi network. Ser-261 is constitutively phosphorylated.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 22q12.1

Cellular Component: Golgi membrane; endoplasmic reticulum membrane

Molecular Function: lipid binding

Biological Process: in utero embryonic development; phospholipid metabolic process; glycerophospholipid biosynthetic process; phospholipid transport; lipid metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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