Human NUDT16 Recombinant Protein – Cat# MBS144262

Nudix Type Motif 16 (NUDT16) Human Recombinant Protein

Name: NUDT16 Recombinant Protein; Nudix Type Motif 16; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144262
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144262

Description: NUDT16 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 215 amino acids (1-195a.a.) and having a molecular mass of 23.4kDa. NUDT16 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nudix Type Motif 16 (NUDT16), Recombinant Protein

Full Product Name

Recombinant Human Nudix Type Motif 16

Product Gene Name

NUDT16 recombinant protein

Product Synonym Names

NUDT16 Human; Nudix Type Motif 16 Human Recombinant; Nudix (nucleoside diphosphate linked moiety X)-Type Motif 16; FLJ31265; FLJ34034; FLJ36248; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme

Sequence

MGSSHHH HHH SSGLVPRGSH MAGARRLELG EALALGSGWR HACHALLYAP DPGMLFGRIP LRYAILMQMR FDGRLGFPGG FVDTQDRSLE DGLNRELREE LGEAAAAFRV ERTDYRSSHV GSGPRVVAHF YAKRLTLEEL LAVEAGATRA KDHGLEVLGL VRVPLYTLRD GVGGLPTFLE NSFIGSAREQ LLEALQDLGL LQSGSISGLK IPAHH

Host

E Coli

Form/Format

The NUDT16 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 1mM DTT, 100mM NaCl and 10% glycerol.
Sterile Filtered clear solution.

Purity/Purification

Greater than 95% as determined by SDS-PAGE.

Preparation and Storage

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles

3D Structure

ModBase 3D Structure for Q96DE0

Product Categories/Family for NUDT16 recombinant protein

Enzymes; Nudix Type Motif

Other Notes

Small volumes of NUDT16 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NUDT16 purchase

MBS144262 is a recombinant protein targeting NUDT16. Also known as Recombinant Human Nudix Type Motif 16. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NUDT16. It may not necessarily be applicable to this product.

NCBI GI #

285026437

NCBI GeneID

131870

NCBI Accession #

NP_001165376.1

UniProt Primary Accession #

Q96DE0

UniProt Secondary Accession #

Q96N82; B4E3B4; E9PED4; F5GYJ1

UniProt Related Accession #

Q96DE0

GenBank Nucleotide #

NM_001171905.1

NCBI Official Full Name

U8 snoRNA-decapping enzyme isoform 3

NCBI Official Synonym Full Names

nudix (nucleoside diphosphate linked moiety X)-type motif 16

NCBI Official Symbol

NUDT16

UniProt Protein Name

U8 snoRNA-decapping enzyme

UniProt Synonym Protein Names

IDP phosphatase (EC:3.6.1.-); IDPase; Inosine diphosphate phosphatase; Nucleoside diphosphate-linked moiety X motif 16; Nudix motif 16; U8 snoRNA-binding protein H29K; m7GpppN-mRNA hydrolase

Protein Family

Nudix hydrolase

UniProt Gene Name

NUDT16

UniProt Synonym Gene Names

IDPase; Nudix motif 16

UniProt Entry Name

NUD16_HUMAN

NCBI Protein Information

U8 snoRNA-decapping enzyme; IDP phosphatase; IDPase; U8 snoRNA-binding protein H29K; inosine diphosphate phosphatase; m7GpppN-mRNA hydrolase; nucleoside diphosphate-linked moiety X motif 16; nudix motif 16

UniProt Comments for NUDT16

NUDT16: RNA-decapping enzyme that binds specifically to U8 snoRNA. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and m227G caps from U8 snoRNA. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species (in vitro). Belongs to the Nudix hydrolase family.

Protein type: Hydrolase; Nucleolus; EC 3.6.1.62

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus

Molecular Function: mRNA binding; snoRNA binding; m7G(5')pppN diphosphatase activity; protein homodimerization activity; GTP binding; metalloexopeptidase activity; manganese ion binding; magnesium ion binding; cobalt ion binding

Biological Process: snoRNA catabolic process; dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; positive regulation of cell proliferation; mRNA catabolic process; proteolysis; adenosine to inosine editing; IDP catabolic process

Research Articles on NUDT16

1. hNUDT16 can also actively cleave the mGDP cap from mRNAs in the presence of Mg(2)(+) or Mn(2)(+).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NUDT16 recombinant protein

Reference Product	PubMed Publications
DCP2 recombinant protein	>3 publications with NUDT16 and DCP2
ITPA recombinant protein	>3 publications with NUDT16 and ITPA

Pathways associated with NUDT16 recombinant protein

Products by Pathway	Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Nucleotides Pathway antibodies	Metabolism Of Nucleotides Pathway Diagram
Phosphate Bond Hydrolysis By NUDT Proteins Pathway antibodies	Phosphate Bond Hydrolysis By NUDT Proteins Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
Purine Metabolism Pathway antibodies	Purine Metabolism Pathway Diagram
RNA Degradation Pathway antibodies	RNA Degradation Pathway Diagram
RNA Degradation Pathway antibodies	RNA Degradation Pathway Diagram

Organs/Tissues associated with NUDT16 recombinant protein

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>1 publications with NUDT16 and Embryonic Tissue
Uterus Antibodies	>1 publications with NUDT16 and Uterus