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Tyrosine Phosphatase Type IVA Member 1 (PTP4A1) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144295

Description: PTP4A1 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 190 amino acids (1-170 a.a.) and having a molecular mass of 21.6kDa. The PTP4A1 is purified… More details

$250 / 0.005 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Tyrosine Phosphatase Type IVA Member 1 (PTP4A1), Recombinant Protein
Full Product Name
Recombinant Human Protein Tyrosine Phosphatase Type IVA Member 1
Product Synonym Names
PTP4A1 Human; Protein Tyrosine Phosphatase Type IVA Member 1 Human Recombinant; Protein tyrosine phosphatase type IVA 1; PTP(CAAXI); Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PRL-1; PTP4A1; PRL1; PTPCAAX1; HH72; DKFZp779M0721
Sequence
MGSSHHH HHH SSGLVPRGSH MARMNRPAPV EVTYKNMRFL ITHNPTNATL NKFIEELKKY GVTTIVRVCE ATYDTTLVEK EGIHVLDWPF DDGAPPSNQI VDDWLSLVKI KFREEPGCCI AVHCVAGLGR APVLVALALI EGGMKYEDAV QFIRQKRRGA FNSKQLLYLE KYRPKMRLRF KDSNGHRNNC
Host
E Coli
Form/Format
The PTP4A1 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Molecular Weight
19,815 Da
OMIM
601585
3D Structure
ModBase 3D Structure for Q93096

Product Categories/Family for PTP4A1 recombinant protein

Other Notes

Small volumes of PTP4A1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTP4A1 purchase

MBS144295 is a recombinant protein targeting PTP4A1. Also known as Recombinant Human Protein Tyrosine Phosphatase Type IVA Member 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for PTP4A1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
protein tyrosine phosphatase type IVA 1
NCBI Official Synonym Full Names
protein tyrosine phosphatase type IVA, member 1
NCBI Official Symbol
PTP4A1
NCBI Official Synonym Symbols
HH72; PRL1; PRL-1; PTPCAAX1; PTP(CAAX1)
UniProt Protein Name
Protein tyrosine phosphatase type IVA 1
UniProt Synonym Protein Names
PTP(CAAXI); Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PRL-1
UniProt Gene Name
PTP4A1
UniProt Synonym Gene Names
PRL1; PTPCAAX1; PRL-1
UniProt Entry Name
TP4A1_HUMAN
NCBI Protein Information
protein tyrosine phosphatase type IVA 1; protein tyrosine phosphatase type IVA protein 1; protein-tyrosine phosphatase 4a1; protein-tyrosine phosphatase of regenerating liver 1

NCBI Summary for PTP4A1

This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013]
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UniProt Comments for PTP4A1

PTP4A1: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. Belongs to the protein-tyrosine phosphatase family.

Protein type: EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6q12

Cellular Component: internal side of plasma membrane; endoplasmic reticulum; early endosome; cytoplasm; spindle

Molecular Function: protein tyrosine phosphatase activity

Biological Process: multicellular organismal development; cell cycle; positive regulation of cell migration
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PTP4A1 recombinant protein

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