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NHP2 Non-Histone Chromosome Protein 2-Like (NHP2L1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144312

Description: NHP2L1 produced in E Coli is a single, non-glycosylated polypeptide chain containing 152 amino acids (1-128a.a.) and having a molecular mass of 16.7kDa.NHP2L1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary… More details

$250 / 0.002 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NHP2 Non-Histone Chromosome Protein 2-Like (NHP2L1), Recombinant Protein
Full Product Name
Recombinant Human NHP2 Non-Histone Chromosome Protein 2-Like
Product Synonym Names
NHP2L1 Human; NHP2 non-histone chromosome protein 2-like Human Recombinant; FA-1; SPAG12; SNRNP15-5; SNU13; 15.5K; U4/U6.U5 tri-snRNP 15.5 kDa protein; NHP2 Non-Histone Chromosome protein 2-like 1 (S. cerevisiae); Sperm Specific Antigen 1; SSFA1; NHPX; FA1; OTK27; High Mobility Group-like Nuclear Protein 2 homolog 1
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMTEADV NPKAYPLADA HLTKKLLDLV QQSCNYKQLR KGANEATKTL NRGISEFIVM AADAEPLEII LHLPLLCEDK NVPYVFVRSK QALGRACGVS RPVIACSVTI KEGSQLKQQI QSIQQSIERL LV
Host
E Coli
Form/Format
The NHP2L1 protein solution (0.25mg/1ml) is formulated in In 20 mM Tris-HCl Buffer (pH 7.5), 100 mM NaCl, and 10% Glycerol.
Sterile Filtered clear solution.
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.
Molecular Weight
14,174 Da
OMIM
601304
3D Structure
ModBase 3D Structure for P55769

Other Notes

Small volumes of NHP2L1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NHP2L1 purchase

MBS144312 is a recombinant protein targeting NHP2L1. Also known as Recombinant Human NHP2 Non-Histone Chromosome Protein 2-Like. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NHP2L1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
NHP2-like protein 1
NCBI Official Synonym Full Names
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NCBI Official Symbol
NHP2L1
NCBI Official Synonym Symbols
FA1; FA-1; NHPX; 15.5K; OTK27; SNU13; SSFA1; SPAG12; SNRNP15-5
UniProt Protein Name
NHP2-like protein 1
UniProt Synonym Protein Names
High mobility group-like nuclear protein 2 homolog 1; OTK27; SNU13 homolog; hSNU13; U4/U6.U5 tri-snRNP 15.5 kDa proteinNHP2-like protein 1, N-terminally processed
UniProt Gene Name
NHP2L1
UniProt Synonym Gene Names
hSNU13
UniProt Entry Name
NH2L1_HUMAN
NCBI Protein Information
NHP2-like protein 1; U4/U6.U5 tri-snRNP 15.5 kDa protein; [U4/U6.U5] tri-snRNP 15.5 kD RNA binding protein; high mobility group-like nuclear protein 2 homolog 1; non-histone chromosome protein 2-like 1; small nuclear ribonucleoprotein 15.5kDa (U4/U6.U5); sperm specific antigen 1

NCBI Summary for NHP2L1

Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for NHP2L1

NHP2L1: Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding. Belongs to the ribosomal protein L7Ae family.

Protein type: RNA splicing; Nucleolus; Spliceosome; RNA-binding

Chromosomal Location of Human Ortholog: 22q13

Cellular Component: nucleoplasm; spliceosome; protein complex; nucleolus; nucleus

Molecular Function: snoRNA binding; protein binding; RNA binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; ribosome biogenesis and assembly; gene expression
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NHP2L1 recombinant protein

Diseases associated with NHP2L1 recombinant protein

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