Human DIRAS1 Recombinant Protein – Cat# MBS144315

DIRAS Family (DIRAS1) Human Recombinant Protein

Name: DIRAS1 Recombinant Protein; DIRAS Family; Human; MyBioSource
Brand: MyBioSource
SKU: MBS144315
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144315

Description: DIRAS1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 215 amino acids (1-195a.a.) and having a molecular mass of 24.1 kDa. DIRAS1 protein is fused to a 20 amino acid His tag at N-terminus and is… More details

$250 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DIRAS family (DIRAS1), Recombinant Protein

Full Product Name

Recombinant Human DIRAS family, GTP-binding RAS-like 1

Product Gene Name

DIRAS1 recombinant protein

Product Synonym Names

DIRAS1 Human; DIRAS family, GTP-binding RAS-like 1 Human Recombinant; GTP-binding protein Di-Ras1; Distinct subgroup of the Ras family member 1; Ras-related inhibitor of cell growth; Rig; Small GTP-binding tumor suppressor 1; DIRAS1; GBTS1; Di-Ras1; FLJ42681

Sequence

MGSSHHH HHH SSGLVPRGSH MPEQSNDYRV VVFGAGGVGK SSLVLRFVKG TFRDTYIPTI EDTYRQVISC DKSVCTLQIT DTTGSHQFPA MQRLSISKGH AFILVFSVTS KQSLEELGPI YKLIVQIKGS VEDIPVMLVG KCDETQREV DTREAQAVAQ EWKCAFMETS AKMNYNVKEL FQELLTLETR RNMSLNIDGK RSGKQKRTDR KGKC

Host

E Coli

Form/Format

DIRAS1 Human solution (1mg/ml) containing 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 1mM DTT, 0.1M NaCl and 1mM EDTA.
Sterile filtered colorless solution.

Purity/Purification

Greater than 95% as determined by SDS-PAGE.

Preparation and Storage

DIRAS1 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.

Molecular Weight

22,329 Da

OMIM

607862

3D Structure

ModBase 3D Structure for O95057

Product Categories/Family for DIRAS1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Member RAS Oncogene Family

Other Notes

Small volumes of DIRAS1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DIRAS1 purchase

MBS144315 is a recombinant protein targeting DIRAS1. Also known as Recombinant Human DIRAS family, GTP-binding RAS-like 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for DIRAS1. It may not necessarily be applicable to this product.

NCBI GI #

21553323

NCBI GeneID

148252

NCBI Accession #

NP_660156.1

UniProt Primary Accession #

O95057

UniProt Related Accession #

O95057

GenBank Nucleotide #

NM_145173.3

NCBI Official Full Name

GTP-binding protein Di-Ras1

NCBI Official Synonym Full Names

DIRAS family, GTP-binding RAS-like 1

NCBI Official Symbol

DIRAS1

NCBI Official Synonym Symbols

RIG; GBTS1; Di-Ras1

UniProt Protein Name

GTP-binding protein Di-Ras1

UniProt Synonym Protein Names

Distinct subgroup of the Ras family member 1; Ras-related inhibitor of cell growth; Rig; Small GTP-binding tumor suppressor 1

Protein Family

GTP-binding protein

UniProt Gene Name

DIRAS1

UniProt Synonym Gene Names

GBTS1; RIG; Rig

UniProt Entry Name

DIRA1_HUMAN

NCBI Protein Information

GTP-binding protein Di-Ras1; distinct subgroup of the Ras family member 1; ras-related inhibitor of cell growth; small GTP-binding tumor suppressor 1

NCBI Summary for DIRAS1

DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004]

UniProt Comments for DIRAS1

DIRAS1: Displays low GTPase activity and exist predominantly in the GTP-bound form. Belongs to the small GTPase superfamily. Di-Ras family.

Protein type: G protein, monomeric, di-Ras; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: plasma membrane

Molecular Function: GTPase activity; GTP binding; mitogen-activated protein kinase binding

Biological Process: positive regulation of MAP kinase activity; metabolic process; small GTPase mediated signal transduction

Research Articles on DIRAS1

1. DIRAS1 downregulation is associated with esophageal squamous cell carcinoma metastasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with DIRAS1 recombinant protein

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>2 publications with DIRAS1 and Nervous System Diseases
Breast Neoplasms Antibodies	>1 publications with DIRAS1 and Breast Neoplasms

Organs/Tissues associated with DIRAS1 recombinant protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with DIRAS1 and Brain
Heart Antibodies	>3 publications with DIRAS1 and Heart
Lymph Antibodies	>1 publications with DIRAS1 and Lymph
Lung Antibodies	>1 publications with DIRAS1 and Lung