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Wd Repeat-Containing Protein WRAP73 (WRAP73) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1443238

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein… More details

$1235 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WD repeat-containing protein WRAP73 (WRAP73), Recombinant Protein
Full Product Name
Recombinant Human WD repeat-containing protein WRAP73 (WRAP73)
Product Gene Name
WRAP73 recombinant protein
Product Synonym Gene Name
WRAP73
Sequence
MNFSEVFKLS SLLCKFSPDG KYLASCVQYR LVVRDVNTLQ ILQLYTCLDQ IQHIEWSADS LFILCAMYKR GLVQVWSLEQ PEWHCKIDEG SAGLVASCWS PDGRHILNTT EFHLRITVWS LCTKSVSYIK YPKACLQGIT FTRDGRYMAL AERRDCKDYV SIFVCSDWQL LRHFDTDTQD LTGIEWAPNG CVLAVWDTCL EYKILLYSLD GRLLSTYSAY EWSLGIKSVA WSPSSQFLAV GSYDGKVRIL NHVTWKMITE FGHPAAINDP KIVVYKEAEK SPQLGLGCLS FPPPRAGAGP LPSSESKYEI ASVPVSLQTL KPVTDRANPK IGIGMLAFSP DSYFLATRND NIPNAVWVWD IQKLRLFAVL EQLSPVRAFQ WDPQQPRLAI CTGGSRLYLW SPAGCMSVQV PGEGDFAVLS LCWHLSGDSM ALLSKDHFCL CFLETEAVVG TACRQLGGHT
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
51,588 Da
Sequence Positions
1-460, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
606040
3D Structure
ModBase 3D Structure for Q9P2S5
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of WRAP73 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WRAP73 purchase

MBS1443238 is a recombinant protein targeting WRAP73. Also known as Recombinant Human WD repeat-containing protein WRAP73 (WRAP73). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for WRAP73. It may not necessarily be applicable to this product.

NCBI GI #
224586777
NCBI GeneID
49856
NCBI Accession #
NP_060288.3
UniProt Primary Accession #
Q9P2S5
UniProt Secondary Accession #
Q5T0D6; Q9BUH7; Q9NTK7; Q9NX56
UniProt Related Accession #
Q9P2S5
GenBank Nucleotide #
NM_017818.3
NCBI Official Full Name
WD repeat-containing protein WRAP73
NCBI Official Synonym Full Names
WD repeat containing, antisense to TP73
NCBI Official Symbol
WRAP73
NCBI Official Synonym Symbols
WDR8
UniProt Protein Name
WD repeat-containing protein WRAP73
UniProt Synonym Protein Names
WD repeat-containing protein 8; WD repeat-containing protein antisense to TP73 gene
Protein Family
WD repeat-containing protein
UniProt Gene Name
WRAP73
UniProt Synonym Gene Names
WDR8
NCBI Protein Information
WD repeat-containing protein WRAP73

UniProt Comments for WRAP73

The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology (PubMed:26545777). Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis; may promote docking of RAB8A- and ARL13B-containing vesicles (PubMed:26675238).
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Research Articles on WRAP73

1. Cep135 is required for the recruitment of WDR8 to centrioles.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with WRAP73 recombinant protein

 Reference Product  PubMed Publications
 VSIG10L recombinant protein  >1 publications with WRAP73 and VSIG10L
 ZNF835 recombinant protein  >1 publications with WRAP73 and ZNF835

Diseases associated with WRAP73 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with WRAP73 and Neoplasms
 Nervous System Diseases Antibodies  >1 publications with WRAP73 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >1 publications with WRAP73 and Congenital Abnormalities
 Abnormalities, Multiple Antibodies  >1 publications with WRAP73 and Abnormalities, Multiple

Organs/Tissues associated with WRAP73 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >2 publications with WRAP73 and Bone
 Connective Tissue Antibodies  >1 publications with WRAP73 and Connective Tissue
 Muscle Antibodies  >1 publications with WRAP73 and Muscle
 Brain Antibodies  >1 publications with WRAP73 and Brain
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