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Dctp Pyrophosphatase 1 (DCTPP1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS144326

Description: DCTPP1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 194 amino acids (1-170) and having a molecular mass of 21.2kDa.DCTPP1 is fused to a 24 amino acid His-tag at N-terminus & purified by… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
dCTP Pyrophosphatase 1 (DCTPP1), Recombinant Protein
Full Product Name
Recombinant Human dCTP Pyrophosphatase 1
Product Gene Name
DCTPP1 recombinant protein
Product Synonym Names
DCTPP1 Human; dCTP Pyrophosphatase 1 Human Recombinant; dCTP pyrophosphatase 1; RS21C6; XTP3TPA; Deoxycytidine-triphosphatase 1; dCTPase 1; XTP3-transactivated gene A protein; CDA03; MGC5627; XTP3-transactivated protein A; EC 3.6.1.12
Sequence
MGSSHHH HHH SSGLVPRGSH MGSHMS VAGG EIRGDTGGED TAAPGRFSFS PEPTLEDIRR LHAEFAAERD WEQFHQPRNL LLALVGEVGE LAELFQWKTD GEPGPQGWSP RERAALQEEL SDVLIYLVAL AARCRVDLPL AVLSKMDINR RRYPAHLARS SSRKYTELPH GAISEDQAVG PADIPCDSTG QTST.
Host
E Coli
Form/Format
The DCTPP1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl and 10% glycerol.
Sterile Filtered colorless solution.
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Preparation and Storage
Store at 4°C if entire vial will be used within 2-4 weeks.
Store at -20°C for longer periods of time.
For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
3D Structure
ModBase 3D Structure for Q9H773

Product Categories/Family for DCTPP1 recombinant protein

Enzymes; Phosphatase

Other Notes

Small volumes of DCTPP1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DCTPP1 purchase

MBS144326 is a recombinant protein targeting DCTPP1. Also known as Recombinant Human dCTP Pyrophosphatase 1. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for DCTPP1. It may not necessarily be applicable to this product.

NCBI GI #
13129100
NCBI GeneID
79077
NCBI Accession #
NP_077001.1
UniProt Primary Accession #
Q9H773
UniProt Related Accession #
Q9H773
GenBank Nucleotide #
NM_024096.1
NCBI Official Full Name
dCTP pyrophosphatase 1
NCBI Official Synonym Full Names
dCTP pyrophosphatase 1
NCBI Official Symbol
DCTPP1
NCBI Official Synonym Symbols
CDA03; RS21C6; XTP3TPA
UniProt Protein Name
dCTP pyrophosphatase 1
UniProt Synonym Protein Names
Deoxycytidine-triphosphatase 1; dCTPase 1; RS21C6; XTP3-transactivated gene A protein
Protein Family
dCTP pyrophosphatase
UniProt Gene Name
DCTPP1
UniProt Synonym Gene Names
XTP3TPA; dCTPase 1
UniProt Entry Name
DCTP1_HUMAN
NCBI Protein Information
dCTP pyrophosphatase 1; XTP3-transactivated gene A protein; XTP3-transactivated protein A; dCTPase 1; deoxycytidine-triphosphatase 1

UniProt Comments for DCTPP1

XTP3TPA: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for modified dCTP. Activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. Hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). Does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP. May protect DNA or RNA against the incorporation of non- canonical nucleotide triphosphates. May protect cells against inappropriate methylation of CpG islands by DNA methyltransferases.

Protein type: EC 3.6.1.12

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: cytosol

Molecular Function: dCTP diphosphatase activity; pyrimidine deoxyribonucleotide binding; magnesium ion binding; nucleoside-triphosphate diphosphatase activity

Biological Process: nucleoside triphosphate catabolic process; protein homotetramerization
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Research Articles on DCTPP1

1. DCTPP1 has a central role in the balance of dCTP and the metabolism of deoxycytidine analogues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DCTPP1 recombinant protein

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram

Organs/Tissues associated with DCTPP1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lymph Antibodies  >1 publications with DCTPP1 and Lymph
 Esophagus Antibodies  >1 publications with DCTPP1 and Esophagus
 Kidney Antibodies  >1 publications with DCTPP1 and Kidney
 Lymph Node Antibodies  >1 publications with DCTPP1 and Lymph Node
 Liver Antibodies  >1 publications with DCTPP1 and Liver
 Lung Antibodies  >1 publications with DCTPP1 and Lung
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